623586-02-7

Basic information

• Product Name: (R)-1,2-DIMETHYL-PIPERAZINE
• Synonyms: (R)-1,2-DIMETHYL-PIPERAZINE;(2R)-1,2-diMethylpiperazine;(R)-1,2-Dimethyl-piperazine dihydrochloride;Piperazine, 1,2-dimethyl-, (2R)-
• CAS NO: 623586-02-7
• Molecular Formula: C₆H₁₄N₂
• Molecular Weight: 114.191
• Mol File: 623586-02-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 147.0±8.0 °C(Predicted)
• Appearance: /
• Density: 0.855±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 9.31±0.40(Predicted)
• CAS DataBase Reference: (R)-1,2-DIMETHYL-PIPERAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1,2-DIMETHYL-PIPERAZINE(623586-02-7)
• EPA Substance Registry System: (R)-1,2-DIMETHYL-PIPERAZINE(623586-02-7)

Safety Data

• Hazardous Substances Data: 623586-02-7(Hazardous Substances Data)

Usage

General Description

(R)-1,2-DIMETHYL-PIPERAZINE is a chemical compound with the molecular formula C6H14N2. It is a piperazine derivative and is used in the pharmaceutical industry as a building block for the synthesis of various drugs and compounds. (R)-1,2-DIMETHYL-PIPERAZINE has a chiral center, and the (R)-enantiomer is the more common form. It is a colorless liquid with a faint amine-like odor and is soluble in water and organic solvents. (R)-1,2-DIMETHYL-PIPERAZINE is mainly used in the synthesis of pharmaceuticals such as antipsychotics, antidepressants, and antihistamines. It is also used as a corrosion inhibitor in some industrial applications.

Upstream product

• 50-00-0 formaldehyd 
• 163765-44-4 (R)-tert-butyl 3-methylpiperazine-1-carboxylate 

Downstream Products

• 623585-99-9 8-({5-chloro-2-[(3R)-3,4-dimethylpiperazin-1-yl]isonicotinoyl}amino)-1-(4-fluoro-phenyl)-4,5-dihydro-1H-benzo[g]indazole-3-carboxamide 
• 1033709-63-5 (5R,6S)-5,6-bis(4-chlorophenyl)-2-[((2S,5R)-2-{[(3R)-3,4-dimethylpiperazin-1-yl]carbonyl}-5-methylpyrrolidin-1-yl)carbonyl]-3-isopropyl-6-methyl-5,6-dihydroimidazo[2,1-b][1,3]thiazole 

Relevant articles and documents

NOVEL SUBSTITUTED IMIDAZOLE DERIVATIVES

The present invention relates to a compound represented by Formula [I] or a pharmaceutically acceptable salt or ester thereof: wherein: X1, X2, X3, and X4, which may be identical or different, are each C or N, provided that none to two of X1, X2, X3, and X4 is/are N; Y is CH or N; R1, R1', R2, R2', R3, R3', R4, and R4', which may be identical or different, are each a hydrogen atom, a lower alkyl group, or the like; R5 is a hydrogen atom or a methyl group; R6 and R7, which may be identical or different, are each a hydrogen atom, a lower alkyl group, or the like; R8 and R8', which may be identical or different, are each a hydrogen atom, a lower alkyl group, or the like; R9 is an aryl group or a heteroaryl group which may be substituted; and n is an integer from 1 to 3, and a PLK1 inhibitor or an anticancer agent containing the same.