62430-05-1 Usage
Description
(5S)5-(2-Methylpropyl)-2-Pyrrolidinone, also known as N-Isobutyl-2-Pyrrolidone or 2-Pyrrolidinone, 5-(2-Methylpropyl)-, (5S)-, is a chemical compound characterized by its molecular formula C9H17NO. (5S)5-(2-Methylpropyl)-2-Pyrrolidinone presents as a clear, colorless to yellow liquid with a faint ammonia-like odor and is miscible with water. Its chemical properties and versatility contribute to its wide range of applications across different industries.
Uses
Used in the Coatings Industry:
(5S)5-(2-Methylpropyl)-2-Pyrrolidinone is used as a solvent for the manufacturing of coatings, facilitating the process by dissolving and carrying the coating components to ensure a uniform and effective application.
Used in the Adhesives Industry:
In the production of adhesives, (5S)5-(2-Methylpropyl)-2-Pyrrolidinone serves as a solvent, enhancing the adhesive's bonding properties and performance by ensuring proper mixing and application of its components.
Used in the Pharmaceutical Industry:
(5S)5-(2-Methylpropyl)-2-Pyrrolidinone is utilized as a solvent in the pharmaceutical sector, playing a crucial role in the formulation and delivery of various medications, including the dissolution of active pharmaceutical ingredients for drug development.
Used in Chemical Synthesis:
As a reaction solvent, (5S)5-(2-Methylpropyl)-2-Pyrrolidinone is employed in chemical synthesis, providing a medium for chemical reactions to occur, which can be critical for the production of specific compounds or materials.
Used in Agricultural Chemicals:
(5S)5-(2-Methylpropyl)-2-Pyrrolidinone is used as a carrier solvent for agricultural chemicals, ensuring the even distribution and application of these chemicals to enhance their effectiveness in crop protection and management.
Used in Industrial Cleaning Processes:
(5S)5-(2-Methylpropyl)-2-Pyrrolidinone is also utilized as a cleaning solvent in industrial processes, where its ability to dissolve a variety of substances makes it an effective agent for cleaning and maintaining equipment and machinery.
Check Digit Verification of cas no
The CAS Registry Mumber 62430-05-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,4,3 and 0 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 62430-05:
(7*6)+(6*2)+(5*4)+(4*3)+(3*0)+(2*0)+(1*5)=91
91 % 10 = 1
So 62430-05-1 is a valid CAS Registry Number.
62430-05-1Relevant articles and documents
Iridium-Catalyzed Enantioselective C(sp3)-H Amidation Controlled by Attractive Noncovalent Interactions
Wang, Hao,Park, Yoonsu,Bai, Ziqian,Chang, Sukbok,He, Gang,Chen, Gong
supporting information, p. 7194 - 7201 (2019/05/10)
While remarkable progress has been made over the past decade, new design strategies for chiral catalysts in enantioselective C(sp3)-H functionalization reactions are still highly desirable. In particular, the ability to use attractive noncovalent interactions for rate acceleration and enantiocontrol would significantly expand the current arsenal for asymmetric metal catalysis. Herein, we report the development of a highly enantioselective Ir(III)-catalyzed intramolecular C(sp3)-H amidation reaction of dioxazolone substrates for synthesis of optically enriched γ-lactams using a newly designed α-amino-acid-based chiral ligand. This Ir-catalyzed reaction proceeds with excellent efficiency and with outstanding enantioselectivity for both activated and unactivated alkyl C(sp3)-H bonds under very mild conditions. It offers the first general route for asymmetric synthesis of γ-alkyl γ-lactams. Water was found to be a unique cosolvent to achieve excellent enantioselectivity for γ-aryl lactam production. Mechanistic studies revealed that the ligands form a well-defined groove-type chiral pocket around the Ir center. The hydrophobic effect of this pocket allows facile stereocontrolled binding of substrates in polar or aqueous media. Instead of capitalizing on steric repulsions as in the conventional approaches, this new Ir catalyst operates through an unprecedented enantiocontrol mechanism for intramolecular nitrenoid C-H insertion featuring multiple attractive noncovalent interactions.
