62452-00-0

Basic information

• Product Name: 3-<3-(N-tert-butoxycarbonylamino)-1-oxopropyl-1-<<5-(4-nitrophenyl)-2-furanyl>methylene>amino>-2,4-imidazolidinedione
• CAS NO: 62452-00-0
• Molecular Weight: 485.453
• Mol File: 62452-00-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-<3-(N-tert-butoxycarbonylamino)-1-oxopropyl-1-<<5-(4-nitrophenyl)-2-furanyl>methylene>amino>-2,4-imidazolidinedione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-<3-(N-tert-butoxycarbonylamino)-1-oxopropyl-1-<<5-(4-nitrophenyl)-2-furanyl>methylene>amino>-2,4-imidazolidinedione(62452-00-0)
• EPA Substance Registry System: 3-<3-(N-tert-butoxycarbonylamino)-1-oxopropyl-1-<<5-(4-nitrophenyl)-2-furanyl>methylene>amino>-2,4-imidazolidinedione(62452-00-0)

Safety Data

• Hazardous Substances Data: 62452-00-0(Hazardous Substances Data)

Upstream product

• 3303-84-2 3-(tert-butyloxycarbonylamino)propionic acid 
• 7261-97-4 dantrolene 

Relevant articles and documents

Synthesis and skeletal muscle relaxant activity of 3-(aminoacyl)-1-[[[5-(substituted phenyl)-2-furanyl]methylene]amino]-2,4-imidazolidinediones

A series of 3-(aminoacyl)-1-[[[5-(substituted phenyl)-2-furanyl]methylene]amino]-2,4-imidazolidinediones was synthesized and evaluated for skeletal muscle relaxant activity. All compounds were active by the intravenous route, and nine of 11 were active orally. One compound was very active when evaluated by the mouse Straub tail and rotarod tests; its efficacy index (ED50 rotarod/ED50Straub tail) was 2.0, while its therapeutic index (LD50/ED50Straub tail) was >225.