6247-15-0

Basic information

• Product Name: 2,3-dihydro-1H-benzo[f]isoindole
• CAS NO: 6247-15-0
• Molecular Formula: C₁₂H₁₁N
• Molecular Weight: 169.2224
• Mol File: 6247-15-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 320.3°C at 760 mmHg
• Flash Point: 160.2°C
• Density: 1.138g/cm³
• Vapor Pressure: 0.00032mmHg at 25°C
• Refractive Index: 1.661
• CAS DataBase Reference: 2,3-dihydro-1H-benzo[f]isoindole(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-dihydro-1H-benzo[f]isoindole(6247-15-0)
• EPA Substance Registry System: 2,3-dihydro-1H-benzo[f]isoindole(6247-15-0)

Safety Data

• Hazardous Substances Data: 6247-15-0(Hazardous Substances Data)

Usage

General Description

2,3-dihydro-1H-benzo[f]isoindole, also known as tetrahydrobenzisoindole, is a chemical compound with a bicyclic structure containing a benzo[f]isoindole core. It is classified as an isoindoline and is commonly found in various pharmaceutical and agrochemical products. 2,3-dihydro-1H-benzo[f]isoindole has been studied for its potential medicinal properties, including its role as an analgesic and antipsychotic agent. It has also been used as a building block in the synthesis of various biologically active compounds. Additionally, 2,3-dihydro-1H-benzo[f]isoindole has been shown to exhibit insecticidal properties, making it a potential candidate for use in insecticides and other agricultural products.

Upstream product

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Relevant articles and documents

Chiral Supramolecular U-Shaped Catalysts Induce the Multiselective Diels-Alder Reaction of Propargyl Aldehyde

The Diels-Alder reaction, which is a traditional [4 + 2] cycloaddition with two carbon-carbon bond formations, is one of the most powerful tools to synthesize versatile and unique six-membered rings. We show that chiral supramolecular U-shaped boron Lewis acid catalysts promote the unprecedented multiselective Diels-Alder reaction of propargyl aldehyde with cyclic dienes. Independent from the substrate control, enantio-, endo/exo-, π-facial-, regio-, site-, and substrate-selectivities could be controlled by the present U-shaped catalysts. The obtained reaction products could access the concise synthesis of chiral diene ligands and a key intermediate of (+)-sarkomycin. The results presented here might partially contribute to the development of artificial enzyme-like supramolecular catalysts for multiselective reactions, which will be able to target organic compounds that have thus far eluded synthesis.