62480-44-8 Usage
Description
H-LEU-AMC HCL, also known as L-Leucine-7-amido-4-methylcoumarin hydrochloride, is a fluorogenic peptidyl substrate used for aminopeptidase activity. It is a white to almost white powder in chemical properties and offers a highly sensitive method for detecting aminopeptidase activity through fluorescence.
Uses
Used in Enzyme Activity Assays:
H-LEU-AMC HCL is used as a fluorogenic substrate for leucine aminopeptidase, providing a highly sensitive method for detecting enzyme activity. The fluorescence detection sensitivity is significantly greater than other methods, such as 4-Methoxy-naphthylamide (pNA) assays.
Used in Aminopeptidase Research:
H-LEU-AMC HCL is used as a sensitive, fluorogenic substrate for aminopeptidases, such as aminopeptidase M. This allows for the study of enzyme kinetics, substrate specificity, and the development of inhibitors or activators for these enzymes.
Used in Pharmaceutical and Biotechnology Industries:
In the pharmaceutical and biotechnology industries, H-LEU-AMC HCL is used as a tool for the development and optimization of drugs targeting aminopeptidases. Its high sensitivity in fluorescence detection makes it an ideal candidate for screening and identifying potential therapeutic agents.
Used in Diagnostic Applications:
H-LEU-AMC HCL can be employed in diagnostic applications to detect and monitor the activity of aminopeptidases in various biological samples. This can be useful in the early detection of diseases or conditions associated with altered aminopeptidase activity.
Used in Academic Research:
In academic research, H-LEU-AMC HCL is used as a valuable tool for studying the structure, function, and regulation of aminopeptidases. This can contribute to a better understanding of the biological roles of these enzymes and their potential as therapeutic targets.
Check Digit Verification of cas no
The CAS Registry Mumber 62480-44-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,4,8 and 0 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 62480-44:
(7*6)+(6*2)+(5*4)+(4*8)+(3*0)+(2*4)+(1*4)=118
118 % 10 = 8
So 62480-44-8 is a valid CAS Registry Number.
InChI:InChI=1/C16H20N2O3.ClH/c1-9(2)6-13(17)16(20)18-11-4-5-12-10(3)7-15(19)21-14(12)8-11;/h4-5,7-9,13H,6,17H2,1-3H3,(H,18,20);1H/t13-;/m0./s1
