625126-88-7

Basic information

• Product Name: Isoquinoline, 1,2,3,4-tetrahydro-5-iodo-2-(trifluoroacetyl)-7-(trifluoroMethyl)-
• Synonyms: Isoquinoline, 1,2,3,4-tetrahydro-5-iodo-2-(trifluoroacetyl)-7-(trifluoroMethyl)-;2,2,2-trifluoro-1-(7-(trifluoroMethyl)-3,4-dihydro-5-iodoisoquinolin-2(1H)-yl)ethanone;2,2,2-Trifluoro-1-(5-iodo-7-(trifluoroMethyl)-3,4-dihydroisoquinolin-2(1H)-yl)ethanone;2,2,2-trifluoro-1-[5-iodo-7-(trifluoromethyl)-3,4-dihydro-1H-isoquinolin-2-yl]ethanone
• CAS NO: 625126-88-7
• Molecular Formula: C₁₂H₈F₆INO
• Molecular Weight: 423.0929092
• EINECS: -0
• Mol File: 625126-88-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Isoquinoline, 1,2,3,4-tetrahydro-5-iodo-2-(trifluoroacetyl)-7-(trifluoroMethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Isoquinoline, 1,2,3,4-tetrahydro-5-iodo-2-(trifluoroacetyl)-7-(trifluoroMethyl)-(625126-88-7)
• EPA Substance Registry System: Isoquinoline, 1,2,3,4-tetrahydro-5-iodo-2-(trifluoroacetyl)-7-(trifluoroMethyl)-(625126-88-7)

Safety Data

• Hazardous Substances Data: 625126-88-7(Hazardous Substances Data)

Usage

General Description

Isoquinoline, 1,2,3,4-tetrahydro-5-iodo-2-(trifluoroacetyl)-7-(trifluoromethyl)- is a chemical compound with a complex structure that includes a heterocyclic isoquinoline ring, a tetrahydro-5-iodo group, and two trifluoroacetyl and trifluoromethyl substituents. It is commonly used in organic synthesis and medicinal chemistry as a building block for the creation of pharmaceuticals and other organic compounds. The presence of the iodo, trifluoroacetyl, and trifluoromethyl groups makes it a versatile starting material for the preparation of a wide range of functionalized molecules with diverse potential biological activities and pharmacological properties.

Upstream product

• 284027-34-5 2,2,2-trifluoro-1-[7-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinolin-2-yl]ethan-1-one 
• 199678-28-9 2,2,2-trifluoro-N-{2-[4-(trifluoromethyl)phenyl]ethyl}acetamide 

Downstream Products

• 625126-96-7 C₁₉H₁₅F₆NOS 

Relevant articles and documents

Heterocyclic cyclopentyl tetrahydroisoquinoline and tetrahydropyridopyridine modulators of chemokine receptor activity

The present invention is directed to compounds of the formula I: Wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, X, n and the broken lines are as defined herein which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.

TETRAHYDROPYRANYL CYCLOPENTYL TETRAHYDROISOQUINOLINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY

The present invention is directed to compounds of the formula I: I(wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n and the dashed line are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.