625394-68-5

Basic information

• Product Name: 8-BROMO-6-METHYL-3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE
• Synonyms: 8-BROMO-6-METHYL-3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE;8-bromo-6-methyl-3,4-dihydro-2H-1,4-benzoxazine
• CAS NO: 625394-68-5
• Molecular Formula: C₉H₁₀BrNO
• Molecular Weight: 228.09
• Mol File: 625394-68-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 310.9±42.0 °C(Predicted)
• Appearance: /
• Density: 1.464±0.06 g/cm3(Predicted)
• PKA: 3.75±0.20(Predicted)
• CAS DataBase Reference: 8-BROMO-6-METHYL-3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 8-BROMO-6-METHYL-3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE(625394-68-5)
• EPA Substance Registry System: 8-BROMO-6-METHYL-3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE(625394-68-5)

Safety Data

• Hazardous Substances Data: 625394-68-5(Hazardous Substances Data)

Upstream product

• 108959-12-2 6-methyl-8-bromo-1,4-benzoxazin-3(2H)-one 
• 20039-91-2 2-bromo-4-methyl-6-nitrophenol 
• 343269-51-2 2-amino-6-bromo-4-methylphenol 

Downstream Products

• 945216-88-6 C₁₅H₁₃BrFNO₃S 
• 945216-89-7 C₂₄H₃₀FN₃O₅S 
• 625394-57-2 8-bromo-4-(4-chloro-benzenesulfonyl)-6-methyl-3,4-dihydro-2H-benzo[1,4]oxazine 

Relevant articles and documents

3,4-Dihydro-2H-benzo[1,4]oxazine derivatives as 5-HT6 receptor antagonists

A series of novel 3,4-dihydro-2H-benzo[1,4]oxazine derivatives has been designed and synthesized as 5-HT6 receptor antagonists. Many of the compounds displayed subnanomolar affinities for the 5-HT6 receptor and good brain penetration in rats. The relationship of structure and lipophilicity to hERG inhibition of this series of compounds is discussed.