62540-98-1Relevant articles and documents
Preparation method of racemic ketoisoleucine calcium and intermediate thereof
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Paragraph 0030; 0032; 0034; 0036; 0038; 0040, (2021/12/07)
The invention relates to a preparation method of racemic ketoisoleucine calcium and an intermediate thereof, the method comprises the following steps: reacting hydantoin and butanone in ammonia water to obtain sec-butyl hydantoin, adding strong base for reaction, and obtaining racemic ketoisoleucine salt with high yield and high purity without complex post-treatment steps. Calcium racemization ketoisoleucine can be prepared by using the calcium racemization ketoisoleucine salt prepared by the method, high-yield and high-purity calcium racemization ketoisoleucine can be obtained, the reaction solvent can be recycled and reused, the method is green and environment-friendly, and the problem of pollution to the environment is solved.