626-76-6 Usage
Description
CIS-NORBIXIN, also known as cis-norbixin, is a natural dye and the principal color component of annatto extract, which is a food coloring agent derived from the seeds of the achiote tree (Bixa orellana). It is known for its vibrant orange-red hue and is widely used in various industries due to its natural and safe properties.
Uses
Used in Food Industry:
CIS-NORBIXIN is used as a natural food coloring agent for imparting a rich orange-red color to various food products. It is favored for its safety, natural origin, and ability to enhance the visual appeal of food items without imparting any significant taste or odor.
Used in Cosmetic Industry:
CIS-NORBIXIN is used as a colorant in cosmetic products, such as lipsticks, creams, and lotions, to provide a natural and vibrant color. Its use in cosmetics is appreciated for its non-toxic nature and ability to add a touch of color without causing any adverse effects on the skin.
Used in Pharmaceutical Industry:
CIS-NORBIXIN is utilized as a coloring agent in pharmaceutical products, including capsules, tablets, and syrups, to improve their appearance and make them more visually appealing to consumers. Its natural origin and safety profile make it a preferred choice for coloring medications.
Used in Textile Industry:
CIS-NORBIXIN serves as a natural dye in the textile industry, where it is used to color fabrics and garments. Its unique color and natural properties make it a popular choice for eco-friendly and sustainable fashion products.
Check Digit Verification of cas no
The CAS Registry Mumber 626-76-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,2 and 6 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 626-76:
(5*6)+(4*2)+(3*6)+(2*7)+(1*6)=76
76 % 10 = 6
So 626-76-6 is a valid CAS Registry Number.
626-76-6Relevant articles and documents
Natural apocarotenoids and their synthetic glycopeptide conjugates inhibit sars-cov-2 replication
Agócs, Attila,Bajusz, Dávid,Batta, Gyula,Bereczki, Ilona,Borbás, Anikó,Hajdú, István,Herczegh, Pál,Hodek, Jan,Jakab, Ferenc,Keser?, Gy?rgy Miklós,Kos, Janko,Kuczmog, Anett,L?rincz, Zsolt,Madai, Mónika,Milánkovits, Márton,Mitrovi?, Ana,Nagy, Veronika,Ostorházi, Eszter,Papp, Henrietta,Weber, Jan,Zsigmond, áron
, (2021/11/08)
The protracted global COVID-19 pandemic urges the development of new drugs against the causative agent SARS-CoV-2. The clinically used glycopeptide antibiotic, teicoplanin, emerged as a potential antiviral, and its efficacy was improved with lipophilic modifications. This prompted us to prepare new lipophilic apocarotenoid conjugates of teicoplanin, its pseudoaglycone and the related ristocetin aglycone. Their antiviral effect was tested against SARS-CoV-2 in Vero E6 cells, using a cell viability assay and quantitative PCR of the viral RNA, confirming their micromolar inhibitory activity against viral replication. Interestingly, two of the parent apocarotenoids, bixin and β-apo-8’carotenoic acid, exerted remarkable anti-SARS-CoV-2 activity. Mechanistic studies involved cathepsin L and B, as well as the main protease 3CLPro, and the results were rationalized by computational studies. Glycopeptide conjugates show dual inhibitory action, while apocarotenoids have mostly cathepsin B and L affinity. Since teicoplanin is a marketed antibiotic and the natural bixin is an approved, cheap and widely used red colorant food additive, these readily available compounds and their conjugates as potential antivirals are worthy of further exploration.
