6263-65-6 Usage
Description
(R)-1-Phenylethanethiol is an organic compound that features a thiol functional group. It is a chiral molecule, with the (R)-configuration indicating the specific arrangement of the atoms in the molecule. (R)-1-Phenylethanethiol is known for its characteristic meat-like, pungent odor, which is reminiscent of (+/–)-1-Phenylethylmercaptan.
Uses
Used in Organic Synthesis:
(R)-1-Phenylethanethiol is used as a source of the thiol functional group in organic synthesis. It plays a crucial role in the formation of alkyl benzylthioethers through S-alkylation, which is an essential process in the synthesis of various organic compounds.
Used in Flavor and Fragrance Industry:
Due to its meat-like, pungent odor, (R)-1-Phenylethanethiol is utilized in the flavor and fragrance industry to create or enhance the aroma of certain products. Its characteristic smell can be used to mimic the scent of cooked meat, making it a valuable component in the development of artificial flavors and fragrances.
Used in the Food Industry:
(R)-1-Phenylethanethiol, or its isomer 2-phenylethanethiole, is reportedly present in mushroom and fermented shrimp and fish paste (trassi). This suggests that it may have applications in the food industry, particularly in enhancing the flavor of these types of products or contributing to the development of new flavor profiles.
Synthesis
No information was found on the synthesis of 1-phenylethylmercaptan, but its isomer, 2-phenylethanethiol, was prepared
from (2-bromoethyl)benzene.
Check Digit Verification of cas no
The CAS Registry Mumber 6263-65-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,6 and 3 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 6263-65:
(6*6)+(5*2)+(4*6)+(3*3)+(2*6)+(1*5)=96
96 % 10 = 6
So 6263-65-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H10S/c1-7(9)8-5-3-2-4-6-8/h2-7,9H,1H3
6263-65-6Relevant articles and documents
Accelerated reduction and solubilization of elemental sulfur by 1,2-aminothiols
Stoffel, Jonathan T.,Riordan, Kimberly T.,Tsui, Emily Y.
supporting information, p. 12488 - 12491 (2021/12/04)
Nucleophilic 1,2-aminothiol compounds readily reduce typically-insoluble elemental sulfur to polysulfides in both water and nonpolar organic solvents. The resulting anionic polysulfide species are stabilized through hydrogen-bonding interactions with the proximal amine moieties. These interactions can facilitate sulfur transfer to alkenes.
Phosphorus pentasulfide mediated conversion of organic thiocyanates to thiols
Maurya, Chandra Kant,Mazumder, Avik,Gupta, Pradeep Kumar
supporting information, p. 1184 - 1188 (2017/07/03)
In this paper we report an efficient and mild procedure for the conversion of organic thiocyanates to thiols in the presence of phosphorus pentasulfide (P2S5) in refluxing toluene. The method avoids the use of expensive and hazardous transition metals and harsh reducing agents, as required by reported methods, and provides an attractive alternative to the existing methods for the conversion of organic thiocyanates to thiols.
Dutch Resolution: Separation of enantiomers with families of resolving agents. A status report
Kellogg, Richard M.,Nieuwenhuijzen, Jose W.,Pouwer,Vries, Ton R.,Broxterman, Quirinus B.,Grimbergen, Reinier F.P.,Kaptein, Bernard,La Crois, Rene M.,De Wever, Ellen,Zwaagstra, Karen,Van Der Laan, Alexander C.
, p. 1626 - 1638 (2007/10/03)
Dutch Resolution is the term given to the use of mixtures (families) of resolving agents in classical resolutions. In this status report an overview is given of the latest results and new (possible) families of resolving agents are introduced. The concept of families is discussed as well as the factors that come into play on use of families. Practical aspects of Dutch Resolution in particular and resolutions in general are discussed.