62639-21-8

Basic information

• Product Name: 4-hydroxy-N-(2-methylphenyl)benzamide
• Synonyms: 4-hydroxy-N-(2-methylphenyl)benzamide;BENZAMIDE, 4-HYDROXY-N-(2-METHYLPHENYL)-
• CAS NO: 62639-21-8
• Molecular Formula: C₁₄H₁₃NO₂
• Molecular Weight: 227.262
• Mol File: 62639-21-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-hydroxy-N-(2-methylphenyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-hydroxy-N-(2-methylphenyl)benzamide(62639-21-8)
• EPA Substance Registry System: 4-hydroxy-N-(2-methylphenyl)benzamide(62639-21-8)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 62639-21-8(Hazardous Substances Data)

Upstream product

• 95-53-4 o-toluidine 
• 99-96-7 4-hydroxy-benzoic acid 
• 54393-58-7 4-(2-methylphenylcarbamoyl)phenyl acetate 

Downstream Products

• 94042-56-5 4-Hydroxy-3,5-bis-pyrrolidin-1-ylmethyl-N-o-tolyl-benzamide 

Relevant articles and documents

Aryl alkyl ether compound as well as derivative, preparation method, pharmaceutical composition and application thereof

The invention discloses an aryl alkyl ether compound as well as a derivative, a preparation method, a pharmaceutical composition and application thereof. The structure of the aryl alkyl ether compound is shown as a formula (I). The aryl alkyl ether compound derivative relates to a stereoisomer, a tautomer, a metabolite, a metabolic precursor, a prodrug, a solvate, a salt of the solvate, a crystal, a pharmaceutically acceptable salt or a mixture of the stereoisomer, the tautomer, the metabolite, the metabolic precursor, the prodrug and the solvate of the aryl alkyl ether compound. The aryl alkyl ether compound and the derivative thereof have a remarkable inhibition effect on indoleamine 2, 3-dioxygenase 1, and can be used for preparing a medicine for treating indoleamine 2, 3-dioxygenase 1 mediated immunosuppression related diseases, and the prepared medicine can exert the medicine effect at the molecular level and is wide in application.

COMPARATIVE STUDIES ON THE PREPARATION OF ISOMERIC HYDROXYBENZAMIDES.

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