6264-67-1

Basic information

• Product Name: 2,4-DIAMINOFLUOROBENZENE
• Synonyms: 5-AMINO-2-FLUOROANILINE;4-FLUORO-BENZENE-1,3-DIAMINE;4-FLUORO-1,3-PHENYLENEDIAMINE;2,4-DIAMINOFLUOROBENZENE;4-Fluoro-1,3-diaminobenzene, 95%;1,3-DIAMINO-4-FLUOROBENZENE;4-Fluoro-1,3-benzenediamine;(5-amino-2-fluoro-phenyl)amine
• CAS NO: 6264-67-1
• Molecular Formula: C₆H₇FN₂
• Molecular Weight: 126.13
• EINECS: 228-426-4
• Product Categories: Anilines, Aromatic Amines and Nitro Compounds
• Mol File: 6264-67-1.mol
• Article Data: 8

Chemical Properties

• Melting Point: 34-37 °C(lit.)
• Boiling Point: 152-153 °C(lit.)
• Flash Point: 221 °F
• Appearance: Black/Powder
• Density: 1.284 g/cm³
• Vapor Pressure: 0.00553mmHg at 25°C
• Refractive Index: 1.625
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: 2,4-DIAMINOFLUOROBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DIAMINOFLUOROBENZENE(6264-67-1)
• EPA Substance Registry System: 2,4-DIAMINOFLUOROBENZENE(6264-67-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 6264-67-1(Hazardous Substances Data)

Usage

General Description

2,4-DIAMINOFLUOROBENZENE is a chemical compound with the molecular formula C6H6F2N2. It is an aromatic amine that is commonly used in the manufacturing of dyes, pharmaceuticals, and organic compounds. 2,4-DIAMINOFLUOROBENZENE is considered to be toxic and can cause irritation to the skin, eyes, and respiratory system upon exposure. 2,4-DIAMINOFLUOROBENZENE is also known to be a potential carcinogen and mutagen, and therefore its use is regulated in many countries. It is important to handle this chemical with care and follow proper safety protocols to prevent any negative health effects.

InChI:InChI=1/C6H7FN2/c7-5-2-1-4(8)3-6(5)9/h1-3H,8-9H2

Upstream product

• 369-36-8 6-fluoro-3-nitroaniline 
• 108-24-7 acetic anhydride 
• 70-34-8 2,4-Dinitrofluorobenzene 
• 364-76-1 4-Fluoro-3-nitroaniline 

Downstream Products

• 67451-21-2 N-[5-(Ethoxyoxalyl-amino)-2-fluoro-phenyl]-oxalamic acid ethyl ester 
• 166818-71-9 4-bromo-6-fluorobenzene-1,3-diamine 
• 740834-97-3 (3-amino-4-fluoro-phenylsulfamoyl)-acetic acid methyl ester 
• 740835-11-4 (3-amino-4-fluoro-phenylsulfamoyl)-acetic acid 
• 1394805-40-3 (R)-N¹-{4-[3-(cyclopropylmethylamino)piperidin-1-yl]-6-propylpyrimidin-2-yl}-4-fluorobenzene-1,3-diamine 

Relevant articles and documents

Preparation method of 1, 2, 4-trifluorobenzene

The invention relates to the technical field of preparation of chemical drug intermediates, and particularly discloses a preparation method of 1, 2, 4trifluorobenzene. The preparation method comprisesthe following steps: step 1, preparing 2, 4-diamino fluorobenzene: carrying out hydrogenation reduction on 2, 4-dinitrofluorobenzene and a catalyst to obtain 2, 4-diamino fluorobenzene with a reaction formula shown in the specification; step 2, preparation of fluoroboric acid diazonium salt: 2, 4-diamino fluorobenzene obtained in the step 1 is subjected to diazotization reaction with a fluoroboric acid aqueous solution and a sodium nitrite aqueous solution in sequence, a fluoroboric acid diazonium salt intermediate is obtained, and the reaction formula is shown in the specification; and step3, preparation of 1, 2, 4-trifluorobenzene: heating and decomposing the fluoroboric acid diazonium salt intermediate obtained in the step 2 to obtain 1, 2, 4-trifluorobenzene, nitrogen and boron trifluoride gas, and the reaction formula is shown in the specification. The method has the advantages that the raw materials are cheap and easy to obtain, the preparation cost is low, the yield is high, few three wastes are produced during preparation, and the economic value of byproducts is high.

A 4, 4 - dimethoxy - 2, 2 - bipyridyl silver catalytic hydrogenation of aromatic nitro compound synthesis of aromatic amines (by machine translation)

The invention discloses a 4, 4 - dimethoxy - 2, 2 - bipyridyl silver catalytic hydrogenation of aromatic nitro compound synthesis of aromatic amines, the method uses a cheap, easy synthesis of 4, 4 - dimethoxy - 2, 2 - bipyridyl silver as catalyst, in order to green, environmental protection, non-toxic as the hydrogen source, the aromatic nitro compound in the relatively mild reaction conditions, one-step reaction can synthesize aromatic amine. The invention has simple operation, catalyst is cheap and easy and small consumption, mild reaction conditions, to substrate demonstrates better functional group tolerant, high product yield, industrial manufacturing cost, it has very good application prospect. (by machine translation)

Synthesis and characterization of highly transparent and hydrophobic fluorinated polyimides derived from perfluorodecylthio substituted diamine monomers

Two new perfluorodecylthio substituted aromatic diamines, namely 2,4-diamino-1-(1H,1H,2H,2H-perfluorodecathio) benzene (DAPFB) and 2,2′-Bis((1H,1H,2H,2H-perfluorodecyl) thio)[1,1′-biphenyl]4,4′-diamine (BPFBD) were synthesized and polycondensed with 4,4′-(hexafluoroisopropylidene)diphthalic anhydride (6FDA) to produce two new perfluorinated polyimides (PI2 and PI4). The chemical structures of these polyimides were confirmed by Fourier transform infrared (FTIR) and nuclear magnetic resonance (NMR) spectroscopy and elemental analysis. Two other polyimides (PI1 and PI3) were also synthesized from 6FDA and analogous perfluorodecylthio unsubstituted diamines to investigate the incorporation effect of perfluorodecylthio group on various physical and chemical properties of the synthesized PIs. Compared with PI1 and PI3, PI2 and PI4 exhibited improved solubility, optical transparency, and hydrophobicity, lower moisture absorption, dielectric constant, and thermo-mechanical stabilities owing to the presence of the perfluorodecylthio side group in the polymer chain. Even though thermo-mechanical properties of PI2 and PI4 (Td5: 413 and 404 °C, Tg: 220 and 209 °C, tensile strength of 101 and 76 MPa, tensile modulus of 1.7 and 1.5 GPa and elongation at break of 8 and 10%, respectively) were reduced in comparison to PI1 and PI3 but still were good enough for most of the practical applications. Most importantly, the presence of the perfluorodecylthio side group in BPFBD considerably reduced the dielectric constant of PI4 to 2.71 which was quite low as aromatic polyimide.