62658-63-3 Usage
Description
2-PROPANOL, 1-[(1,1-DIMETHYLETHYL)AMINO]-3-[(2-METHYL-1H-INDOL-4-YL)OXY]-, BENZOATE (ESTER) is a complex organic compound with a unique chemical structure. It is characterized by its off-white to pale yellow solid appearance and is related to the chemical class of esters. 2-PROPANOL, 1-[(1,1-DIMETHYLETHYL)AMINO]-3-[(2-METHYL-1H-INDOL-4-YL)OXY]-, BENZOATE (ESTER) is derived from 2-propanol and features a 1,1-dimethylethylamino group, a 2-methyl-1H-indol-4-yloxy group, and a benzoate ester group. Its chemical properties and structure make it a potential candidate for various applications in different industries.
Uses
Used in Pharmaceutical Industry:
2-PROPANOL, 1-[(1,1-DIMETHYLETHYL)AMINO]-3-[(2-METHYL-1H-INDOL-4-YL)OXY]-, BENZOATE (ESTER) is used as an active pharmaceutical ingredient for the development of long-acting β-adrenoceptor blocking agents. It is particularly useful in the treatment of hypertension due to its potent and long-lasting effects. 2-PROPANOL, 1-[(1,1-DIMETHYLETHYL)AMINO]-3-[(2-METHYL-1H-INDOL-4-YL)OXY]-, BENZOATE (ESTER)'s unique structure allows it to have negligible effects on serum lipoproteins, making it a valuable option for patients with hypertension.
Used in Antispasmogenic Applications:
In the medical field, 2-PROPANOL, 1-[(1,1-DIMETHYLETHYL)AMINO]-3-[(2-METHYL-1H-INDOL-4-YL)OXY]-, BENZOATE (ESTER) is used as an antispasmogenic agent, mediating its effects through α1-adrenoceptors and 5-HT2 receptors. This application can be beneficial in treating various conditions characterized by involuntary muscle contractions or spasms.
Used in Chemical Research:
Due to its unique chemical structure, 2-PROPANOL, 1-[(1,1-DIMETHYLETHYL)AMINO]-3-[(2-METHYL-1H-INDOL-4-YL)OXY]-, BENZOATE (ESTER) can be utilized in chemical research for the development of new compounds and materials. Its properties may be of interest to researchers working on the synthesis of novel pharmaceuticals, agrochemicals, or other specialty chemicals.
Brand Name:
The brand name for 2-PROPANOL, 1-[(1,1-DIMETHYLETHYL)AMINO]-3-[(2-METHYL-1H-INDOL-4-YL)OXY]-, BENZOATE (ESTER) is SANDONORM, which may be used to market the compound for its various applications in the pharmaceutical and medical industries.
Originator
sandoz (Switzerland)
Manufacturing Process
4-(2-Benzoyloxy-3-t-butylaminopropoxy)-2-methyl-indole:
26 g of benzoic acid are dissolved, while heating, in 50 ml of
hexamethylphosphoric acid triamide and 3.5 g of 1-t-butylamino-3-(2-methylindole-
4-yloxy)-2-propanol are added. After cooling, 3.0 g of benzoic acid
anhydride are added and stirred for 20 hours at room temperature. The
resulting clear, yellow solution is poured onto ice 0.5 liters of ether are added
and stirred for 2 hours. After making the liquid alkaline with concentrated
ammonia, the ether phase is separated, shaken out with tartaric acid, made
alkaline with caustic soda solution while cooling with ice and extracted with
methylene chloride. After evaporating the solvent, the residue is crystallized
with 1 mol of fumaric acid from methanol and acetone.
Therapeutic Function
Beta-adrenergic blocker
Check Digit Verification of cas no
The CAS Registry Mumber 62658-63-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,2,6,5 and 8 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 62658-63:
(7*6)+(6*2)+(5*6)+(4*5)+(3*8)+(2*6)+(1*3)=143
143 % 10 = 3
So 62658-63-3 is a valid CAS Registry Number.
InChI:InChI=1/C23H28N2O3/c1-16-13-19-20(25-16)11-8-12-21(19)27-15-18(14-24-23(2,3)4)28-22(26)17-9-6-5-7-10-17/h5-13,18,24-25H,14-15H2,1-4H3
