62663-27-8

Basic information

• Product Name: 3-(2-phenyl-1H-indol-3-yl)propanoic acid
• Synonyms: 3-(2-phenyl-1H-indol-3-yl)propanoic acid
• CAS NO: 62663-27-8
• Molecular Formula: C₁₇H₁₅NO₂
• Molecular Weight: 265.31
• Mol File: 62663-27-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 530.6 °C at 760 mmHg
• Flash Point: 274.7 °C
• Appearance: /
• Density: 1.256 g/cm³
• Vapor Pressure: 4.34E-12mmHg at 25°C
• Refractive Index: 1.67
• CAS DataBase Reference: 3-(2-phenyl-1H-indol-3-yl)propanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-phenyl-1H-indol-3-yl)propanoic acid(62663-27-8)
• EPA Substance Registry System: 3-(2-phenyl-1H-indol-3-yl)propanoic acid(62663-27-8)

Safety Data

• Hazardous Substances Data: 62663-27-8(Hazardous Substances Data)

Usage

General Description

3-(2-phenyl-1H-indol-3-yl)propanoic acid is a chemical compound with a molecular formula C18H17NO2. It belongs to the class of compounds known as indole derivatives, which are widely used in the pharmaceutical and chemical industries. 3-(2-phenyl-1H-indol-3-yl)propanoic acid is a derivative of indole, a heterocyclic aromatic organic compound, and propanoic acid, a carboxylic acid. 3-(2-phenyl-1H-indol-3-yl)propanoic acid has potential applications in medicinal chemistry, particularly for its anti-inflammatory and analgesic properties. 3-(2-phenyl-1H-indol-3-yl)propanoic acid may also be used as a building block in the synthesis of other biologically active molecules.

InChI:InChI=1/C17H15NO2/c19-16(20)11-10-14-13-8-4-5-9-15(13)18-17(14)12-6-2-1-3-7-12/h1-9,18H,10-11H2,(H,19,20)

Upstream product

• 100-63-0 phenylhydrazine 
• 1501-05-9 5-oxo-5-phenylvaleric acid 
• 591-50-4 iodobenzene 
• 830-96-6 Indole-3-propionic acid 
• 98-86-2 acetophenone 
• 948-65-2 2-phenyl-indole 
• 79-10-7 acrylic acid 
• 583-11-9 N-(1-phenylethylidene)phenylhydrazine 

Downstream Products

• 785795-31-5 3-(2-phenyl-1H-indol-3-yl)-propionamide 
• 785795-32-6 [3-(2-phenyl-1H-indol-3-yl)-propyl]-carbamic acid tert-butyl ester 
• 785795-34-8 3-[3-(3-amino-propyl)-2-phenyl-indol-1-yl]-propionic acid methyl ester 
• 785795-35-9 3-[3-(3-methanesulfonylamino-propyl)-2-phenyl-indol-1-yl]-propionic acid methyl ester 
• 785795-36-0 3-[3-(3-methanesulfonylamino-propyl)-2-phenyl-indol-1-yl]-propionic acid 
• 785795-33-7 3-[3-(3-tert-butoxycarbonylamino-propyl)-2-phenyl-1H-indol-1-yl]-propionic acid methyl ester 
• 785795-46-2 3-[3-(3-tert-butoxycarbonylamino-propyl)-2-phenyl-indol-1-yl]-propionic acid methyl ester 
• 137116-97-3 3-(2-phenyl-1H-indol-3-yl)-propylamine 

Relevant articles and documents

Synthesis and antimicrobial activity of new series of 2-phenyl-3-[2-(5-substituted-1,3,4-oxadiazol-2-yl) ethyl]-1H-indoles

This research article presents the synthesis and antimicrobial activity of a new series of 2-phenyl-3-[2-(5-substituted-1,3,4-oxadiazol-2-yl) ethyl]-1H-indoles 5(a-f). The structures of the compounds were confirmed by FT-IR, 1H NMR and Mass spectral data. All the derivatives have shown moderate to excellent antimicrobial activities. 5a has shown remarkable Minimum Inhibitory Concentration especially against Bacillus subtilis, Klebsiella pneumoniae, Candida albicans, Aspergillus niger when compared with the standard drugs.

Combinatorial synthesis of substituted 3-(2-indolyl)piperidines and 2-phenyl indoles as inhibitors of ZipA-FtsZ interaction

The ZipA-FtsZ protein-protein interaction is a potential target for antibacterial therapy. The design and parallel synthesis of a combinatorial library of small molecules, which target the FtsZ binding area on ZipA are described. Compounds were demonstrat