6270-74-2

Basic information

• Product Name: (3-OXO-3,4-DIHYDRO-2H-1,4-BENZOTHIAZIN-2-YL)ACETIC ACID
• Synonyms: 3,4-DIHYDRO-3-OXO-2H-(1,4)-BENZOTHIAZIN&;3,4-Dihydro-3-oxo-2H-1,4-benzothiazine-2-acetic acid, 97%;3-Oxo-3,4-dihydro-2H-1,4-benzothiazine-2-acetic acid, 97%;(3-Oxo-3,4-dihydro-2H-benzo[1,4]thiazin-2-yl)-acetic;2-(3-keto-4H-1,4-benzothiazin-2-yl)acetic acid;2-(3-oxo-4H-1,4-benzothiazin-2-yl)acetic acid;2-(3-oxo-4H-1,4-benzothiazin-2-yl)ethanoic acid;2H-1,4-Benzothiazine-2-acetic acid, 3,4-dihydro-3-oxo-
• CAS NO: 6270-74-2
• Molecular Formula: C₁₀H₉NO₃S
• Molecular Weight: 223.25
• Product Categories: Building Blocks;Heterocyclic Building Blocks;Thiazines;Building Blocks;Chemical Synthesis;Heterocyclic Building Blocks
• Mol File: 6270-74-2.mol
• Article Data: 9

Chemical Properties

• Melting Point: 182-186 °C(lit.)
• Boiling Point: 509.9 °C at 760 mmHg
• Flash Point: 262.2 °C
• Appearance: /
• Density: 1.391 g/cm³
• Vapor Pressure: 3.21E-11mmHg at 25°C
• CAS DataBase Reference: (3-OXO-3,4-DIHYDRO-2H-1,4-BENZOTHIAZIN-2-YL)ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (3-OXO-3,4-DIHYDRO-2H-1,4-BENZOTHIAZIN-2-YL)ACETIC ACID(6270-74-2)
• EPA Substance Registry System: (3-OXO-3,4-DIHYDRO-2H-1,4-BENZOTHIAZIN-2-YL)ACETIC ACID(6270-74-2)

Safety Data

• Hazard Codes: Xi
• Statements: 43
• Safety Statements: 36/37
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 6270-74-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H9NO3S/c12-9(13)5-8-10(14)11-6-3-1-2-4-7(6)15-8/h1-4,8H,5H2,(H,11,14)(H,12,13)/p-1/t8-/m1/s1

Upstream product

• 106660-02-0 (Z)-(3'-oxo-3',4'-dihydro-2'H-1',4'-benzothiazin-2'-ylidene)acetic acid 
• 110-16-7 maleic acid 
• 137-07-5 2-amino-benzenethiol 
• 110-17-8 (2E)-but-2-enedioic acid 
• 923-06-8 bromosuccinic acid 
• 7028-52-6 (4-hydroxy-3-oxo-3,4-dihydro-2H-benzo[1,4]thiazin-2-yl)-acetic acid 
• 108-31-6 maleic anhydride 
• 64-17-5 ethanol 
• 90704-68-0 2'-mercapto maleianilic acid 
• 3052-50-4 monomethyl maleate 
• 2756-87-8 methyl hydrogen fumarate 
• 7291-93-2 (2-nitro-phenylsulfanyl)-succinic acid dimethyl ester 

Downstream Products

• 97021-05-1 1-Thio-phenmorpholon-(3)-essigsaeure-(2)-(2-diethylamino-ethylester) 
• 82191-17-1 ethyl 2-(3,4-dihydro-3-oxo-2H-1,4-benzothiazin-2-yl)acetate 
• 2694-31-7 1-phenyl-3,3a-dihydro-1H-benzo[b]pyrrolo[2,3-e][1,4]thiazin-2-one 
• 2694-32-8 1-(4-methoxy-phenyl)-3,3a-dihydro-1H-benzo[b]pyrrolo[2,3-e][1,4]thiazin-2-one 
• 106691-40-1 N-(3-chlorophenyl)-2-(3-oxo-1,4-benzothiazin-2-yl) acetamide 
• 101350-88-3 (3-oxo-3,4-dihydro-2H-benzo[1,4]thiazin-2-yl)-acetic acid anilide 
• 134616-46-9 2-(3-Oxo-3,4-dihydro-2H-benzo[1,4]thiazin-2-yl)-N-m-tolyl-acetamide 
• 106691-37-6 2-(3-Oxo-3,4-dihydro-2H-benzo[1,4]thiazin-2-yl)-N-p-tolyl-acetamide 
• 134616-47-0 1-o-Tolyl-3,3a-dihydro-1H-benzo[b]pyrrolo[2,3-e][1,4]thiazin-2-one 
• 134616-49-2 1-p-Tolyl-3,3a-dihydro-1H-benzo[b]pyrrolo[2,3-e][1,4]thiazin-2-one 
• 134616-48-1 1-m-Tolyl-3,3a-dihydro-1H-benzo[b]pyrrolo[2,3-e][1,4]thiazin-2-one 
• 134616-50-5 1-(3-chlorophenyl)-2-oxo-1,2,3,3a-H-tetrahydropyrrolo<3,2-b><1,4> benzothiazine 
• 134616-45-8 2-(3-Oxo-3,4-dihydro-2H-benzo[1,4]thiazin-2-yl)-N-o-tolyl-acetamide 
• 106691-38-7 N-(4-Methoxy-phenyl)-2-(3-oxo-3,4-dihydro-2H-benzo[1,4]thiazin-2-yl)-acetamide 

Relevant articles and documents

Sulfuryl Chloride Promoted gem -Dichlorination-Dehydrochlorination in Alkyl Benzothiazinylacetates: Synthesis of the Skeleton of Trichochrome Pigments

Chemo- and stereoselective total synthesis of the basic trichochrome skeleton is described starting from o-aminothiophenol and maleic anhydride in very good overall yield. The process involves the synthesis of the corresponding 1,4-benzothiazin-2-ylacetates followed by their sulfuryl chloride induced dihalogenation-dehydrohalogenation and a second condensation with o-aminothiophenol as key steps.

PEPTIDE DEFORMYLASE INHIBITORS

Benzothiazine compounds of the general formula (I) and pharmaceutically acceptable salts or esters thereof are peptide deformylase inhibitors useful in the treatment or prevention of infections and other diseases in which peptide deformylases are involved

Synthesis and characterization of cobalt(II), nickel(II), copper(II) and palladium(II) complexes of polydentate ligands

A few complexes of Co(II), Ni(II), Cu(II) and Pd(II) with a tetradentate ligand N,N'-ethylene-bis-(3-carboxypropenamide) and a bidentate ligand benz--2-carboxymethyl-1,3,4-thiolactam have been synthesised and characterized by elemental analyses, conductance, thermal, magnetic and IR, NMR and electronic spectral studies.