62702-03-8Relevant articles and documents
Amberlyst-15: A reusable heterogeneous catalyst for the dehydration of tertiary alcohols
Frija, Luís M.T.,Afonso, Carlos A.M.
, p. 7414 - 7421 (2012/09/22)
Tertiary alcohols react under mild conditions in the presence of Amberlyst-15 (dry) (solid-supported sulfonic acid) to give predominantly the most stable alkene in very good yield. The dehydration of tertiary alcohol functionality occurs without observation of rearrangement and polymerization products, and with outstanding substrate tolerance, which include the NHCBz, NHBoc, OSEM, OTBDMS, OBOM and ethylene ketal functional groups. Amberlyst-15 (dry) can be easily recovered from the reaction medium and reused for five cycles, maintaining the catalytic efficiency. In addition, the dehydration can occur under continuous operation.
Suzuki-Miyaura cross-coupling of lithium n-alkylborates
Zou, Gang,Falck
, p. 5817 - 5819 (2007/10/03)
The palladium-catalyzed cross-coupling of lithium n-alkylborates, generated in situ via addition of sec-butyl lithium to boronate esters, proceeds in moderate to good yields with a wide variety of electrophiles.
The first general method for palladium-catalyzed Negishi cross-coupling of aryl and vinyl chlorides: Use of commercially available Pd(P(t-Bu)3)2 as a catalyst
Dai,Fu
, p. 2719 - 2724 (2007/10/03)
With a single protocol, commercially available Pd(P(t-Bu)3)2 can effect the Negishi cross-coupling of a wide range of aryl and vinyl chlorides with aryl- and alkylzinc reagents. The process tolerates nitro groups, and it efficiently generates sterically hindered biaryls. In addition, a high turnover number (>3000) can be achieved.