62720-30-3

Basic information

• Product Name: 5-BroMo-1,3-dichloro-2-iodobenzene
• Synonyms: 5-BroMo-1,3-dichloro-2-iodobenzene
• CAS NO: 62720-30-3
• Molecular Formula: C₆H₂BrCl₂I
• Molecular Weight: 351.79455
• Mol File: 62720-30-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 67.8-68.7 °C
• Boiling Point: 314.2±37.0 °C(Predicted)
• Appearance: /
• Density: 2.320±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 5-BroMo-1,3-dichloro-2-iodobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BroMo-1,3-dichloro-2-iodobenzene(62720-30-3)
• EPA Substance Registry System: 5-BroMo-1,3-dichloro-2-iodobenzene(62720-30-3)

Safety Data

• Hazardous Substances Data: 62720-30-3(Hazardous Substances Data)

Usage

Description

5-Bromo-1,3-dichloro-2-iodobenzene is a chemical compound with the molecular formula C6H3BrCl2I. It is a derivative of benzene, containing bromine, chlorine, and iodine atoms attached to its structure.
Used in Pharmaceutical Industry:
5-Bromo-1,3-dichloro-2-iodobenzene is used as an intermediate in the synthesis of various pharmaceuticals for its ability to be incorporated into complex organic molecules.
Used in Agrochemical Industry:
5-Bromo-1,3-dichloro-2-iodobenzene is used as an intermediate in the synthesis of various agrochemicals for its potential to be part of compounds that can be used in agricultural applications.
Used in Organic Synthesis:
5-Bromo-1,3-dichloro-2-iodobenzene is used as a building block for more complex compounds, contributing to the development of new chemical entities with diverse applications.

Upstream product

• 697-88-1 4-bromo-2,6-dichloroaniline 
• 608-31-1 2,6-Dichloroaniline 

Downstream Products

• 19752-55-7 1-bromo-3,5-dichlorobenzene 
• 848758-08-7 3,5-dichloro-4-trimethylsilyl-bromobenzene 

Relevant articles and documents

Electrochemical reductive cleavage of carbon-halogen bonds in 5-bromo-1,3-dichloro-2-iodobenzene

The electrochemical reduction of carbon-halogen bonds in 5-bromo-1,3-dichloro-2-iodobenzene follows quadratic activation-driving force relationship except in one of the carbon-chlorine bonds. The variation of the transfer coefficient with the electrode potential has been estimated using the voltammetric data coupled with the convolution analysis. The standard potentials pertaining to the reduction of carbon-halogen bonds are evaluated using the Marcus theory of outer sphere electron transfer.

Nucleophilic Displacement in Polyhalogenoaromatic Compounds. Part 11. Kinetics of Protiodeiodination of Iodoarenes in Dimethyl Sulphoxide-Methanol

The rates of methoxide-ion induced protiodeiodination of a number of polychloroiodobenzenes and their derivatives have been measured in dimethyl sulphoxide-methanol (9:1 v/v; 323.2 K).The true reagent under these conditions appears to be the dimethyl sulphoxide anion, and the rates of reaction in some cases appear to approach that expected of a diffusion controlled process.This corresponds to a major decrease in the efficacy of further activating substituents in the aromatic system, altough deactivating groups such as p-OMe still show large effects.Chlorine promotes protiodeiodination in the order of efficiency o-Cl > m-Cl > p-Cl; the trifluoromethyl group activates displacement in the order o-CF3 > p-CF3 > m-CF3, although with much less difference between isomeric sites. o-Nitro-groups promote protiodeiodination whereas the p-nitro-group encourages methoxydeiodination.No evidence of methoxydeiodination was found in attack of the polychloroiodobenzenes, although the rates of methoxydechlorination of the corresponding polychlorobenzenes suggest that in some cases this might occur.Evidence rejecting the possible SRN1 mechanism and supporting nucleophilic attack by a carbanionic species upon iodine is presented.