6273-57-0

Basic information

• Product Name: purpurogallin tetramethyl ether
• Synonyms: purpurogallin tetramethyl ether
• CAS NO: 6273-57-0
• Molecular Formula: C₁₅H₁₆O₅
• Molecular Weight: 276.28454
• Mol File: 6273-57-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 483.7°C at 760 mmHg
• Flash Point: 217°C
• Appearance: /
• Density: 1.22g/cm³
• Vapor Pressure: 1.64E-09mmHg at 25°C
• Refractive Index: 1.561
• CAS DataBase Reference: purpurogallin tetramethyl ether(CAS DataBase Reference)
• NIST Chemistry Reference: purpurogallin tetramethyl ether(6273-57-0)
• EPA Substance Registry System: purpurogallin tetramethyl ether(6273-57-0)

Safety Data

• Hazardous Substances Data: 6273-57-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H16O5/c1-17-10-7-5-6-9-8-11(18-2)14(19-3)15(20-4)12(9)13(10)16/h5-8H,1-4H3

Upstream product

• 569-77-7 purpurogallin 
• 77-78-1 dimethyl sulfate 
• 616-42-2 dimethylsulfite 
• 15795-64-9 4-hydroxy-2,3,6-trimethoxy-5H-benzo[7]annulen-5-one 
• 74-88-4 methyl iodide 

Downstream Products

• 15795-64-9 4-hydroxy-2,3,6-trimethoxy-5H-benzo[7]annulen-5-one 
• 50276-60-3 3,4,5-trimethoxyphthalic acid 

Relevant articles and documents

Synthesis and evaluation as potential anticancer agents of novel tetracyclic indenoquinoline derivatives

We report the synthesis and evaluation as potential anticancer agents of a series of tetracyclic indenoquinolines. The compounds, which are obtained through the photoisomerization of Diels-Alder adducts formed between purpurogallin derivatives and nitrosobenzene, have in vitro antiproliferative activities in the μM to nM range against breast (MCF-7), lung epithelial (A-549), and cervical (HeLa) adenocarcinoma cells. The cytotoxicities of several of the novel tetracycles are comparable to or better than that of camptothecin. A strong correlation between the activity of the compounds and their aromaticity and planarity was observed, suggesting a mode of action similar to that of topoisomerase poisons.

Synthesis and in vitro protozoocidal activity of diazabicyclic benzotropolone derivatives

We describe the synthesis and protozoocidal evaluation of a series of diazabicycles based on benzotropolone ethers. Several of the compounds, which can be obtained through a high-yielding hetero Diels-Alder reaction using simple and readily available star