6274-00-6

Basic information

• Product Name: 4-methyl-3-(2-oxo-2-phenylethyl)-1,3-thiazol-3-ium
• CAS NO: 6274-00-6
• Molecular Formula: Br*C₁₂H₁₂NOS
• Molecular Weight: 218.2942
• Mol File: 6274-00-6.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 4-methyl-3-(2-oxo-2-phenylethyl)-1,3-thiazol-3-ium(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-3-(2-oxo-2-phenylethyl)-1,3-thiazol-3-ium(6274-00-6)
• EPA Substance Registry System: 4-methyl-3-(2-oxo-2-phenylethyl)-1,3-thiazol-3-ium(6274-00-6)

Safety Data

• Hazardous Substances Data: 6274-00-6(Hazardous Substances Data)

Usage

General Description

4-methyl-3-(2-oxo-2-phenylethyl)-1,3-thiazol-3-ium is a chemical compound with a molecular formula of C12H13NOS. It is a derivative of thiazole, a five-membered heterocyclic compound containing both sulfur and nitrogen in the ring. The compound contains a thiazolium cation, which is a positively charged ion with a thiazole ring and an attached 2-oxo-2-phenylethyl group. Thiazolium compounds have been investigated for their potential biological activities, including antimicrobial and antitumor properties. This specific compound's structure indicates that it may have potential applications in medicinal and pharmaceutical chemistry due to its unique substitution pattern and potential reactivity.

Upstream product

• 693-95-8 4-Methylthiazole 
• 70-11-1 α-bromoacetophenone 

Downstream Products

• 57132-49-7 5ξ-benzoyl-3-methyl-7-phenyl-(5ar,8ac,8bt)-5,5a,8a,8b-tetrahydro-pyrrolo[3',4':3,4]pyrrolo[2,1-b]thiazole-6,8-dione 
• 57132-50-0 4-methyl-3-(2-oxo-2-phenyl-1-phenylcarbamoyl-ethyl)-thiazolium betaine 
• 57132-51-1 4-methyl-3-[2-oxo-2-phenyl-1-(phenyl-thiocarbamoyl)-ethyl]-thiazolium betaine 
• 57132-34-0 1-(cis-2-ethoxycarbonyl-vinyloxy)-4-methyl-1-phenyl-1H-pyrrolo[2,1-c][1,4]thiazine-7-carboxylic acid ethyl ester 
• 57132-30-6 Dimethyl 1-hydroxy-4-methyl-1-phenyl-1H-pyrrolo<2,1-c>-1,4-thiazine-7,8-dicarboxylate 
• 57132-38-4 1-(cis-2-carboxy-vinyloxy)-4-methyl-1-phenyl-1H-pyrrolo[2,1-c][1,4]thiazine-7-carboxylic acid 
• 1217299-46-1 5-benzoyl-3-methylpyrrolo[2,1-b]thiazole-7-carbonitrile 
• 1217299-47-2 methyl 5-benzoyl-3-methylpyrrolo[2,1-b]thiazole-7-carboxylate 
• 1310572-69-0 5-benzoyl-3-methylpyrrolo[2,1-b]thiazole-7-carboxylic acid 

Relevant articles and documents

Synthesis and antiproliferative activity of multisubstituted N-fused heterocycles against the Hep-G2 cancer cell line

Pyrrolo[1,2-a]imidazole and pyrrolo[2,1-b]thiazole derivatives were synthesized in a one-pot procedure by [3 + 2] cycloaddition reactions of the corresponding imidazolium ylides and thiazolium ylides with an alkene followed by oxidative aromatization of t

Method and composition for rejuvenating hair, nails, tissues, cells and organs by ex-vivo or immersive treatment

A method and composition for the treatment of hair, nail, ex-vivo organ, ex-vivo cell or ex-vivo tissue to improve the biomechanical and diffusional characteristics comprising an effective amount of a compound selected from the group consisting of compounds of the formula

Preventing and reversing the formation of advanced glycosylation endproducts

The present invention relates to compositions and methods for inhibiting and reversing nonenzymatic cross-linking (protein aging). Accordingly, compositions are disclosed which comprise an agent capable of inhibiting the formation of advanced glycosylation endproducts of target proteins, and which additionally reverse pre-formed crosslinks in the advanced glycosylation endproducts by cleaving alpha-dicarbonyl-based protein crosslinks present in the advanced glycosylation endproducts. Certain agents useful are thiazolium salts. The method comprises contacting the target protein with the composition. Both industrial and therapeutic applications for the invention are envisioned, as food spoilage and animal protein aging can be treated. A novel immunoassay for detection of the reversal of the nonenzymatic crosslinking is also disclosed.