6275-29-2Relevant articles and documents
Ligand design for alpha1 adrenoceptor subtype selective antagonists.
Bremner,Coban,Griffith,Groenewoud,Yates
, p. 201 - 214 (2000)
Alpha1 adrenoceptors have three subtypes and drugs interacting selectively with these subtypes could be useful in the treatment of a variety of diseases. In order to gain an insight into the structural principles governing subtype selectivity, ligand base
BERBERIS ALKALOIDS. XXIX. AN INVESTIGATION OF THE ALKALOIDS OF Berberis sibirica
Karimov, A.,Levkovich, M. G.,Abdullaev, N. D.,Shakirov, R.
, p. 361 - 364 (1993)
The alkaloid compositions of the roots, young shoots, and leaves of Berberis sibirica have been studied, and berberine, palmatine, columbamine, berberrubine, oxyacanthine, berbamine, 8-oxoberberine, 8-oxoberrberubine, pakistanine, and pronunciferine, and
Stereoselective total synthesis of (S)- and (R)-nuciferine using benzyne chemistry
Casagrande, Gleison A.,Deflon, Victor M.,Martins, Gabriel R.,Oliveira-Silva, Diogo,Perecim, Givago P.,Pinto, Leandro M. C.,Raminelli, Cristiano
, (2020/08/13)
Total syntheses of (S)- and (R)-nuciferine were accomplished through approach involving diastereoselective reaction between a chiral dihydroisoquinoline enamide and 2-(trimethylsilyl)phenyl trifluoromethanesulfonate promoted by CsF, affording a separable mixture of diastereoisomers, which provided (S)- and (R)-nuciferine via simple and efficient transformations.
Preparation method of compound 5,6-dihydroxy indoline and halogen acid salts thereof
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Paragraph 0050-0053; 0073, (2018/04/01)
The invention relates to a preparation method of a compound 5,6-dihydroxy indoline and halogen acid salts thereof. Phenylethylamine SM-0 sold in the market is used as a raw material and firstly reactswith acyl chloride to obtain amide SM-1; amide SM-1 rea