62778-20-5

Basic information

• Product Name: 1-THIO-D-GLUCOSE SODIUM SALT
• Synonyms: SODIUM THIOGLUCOSE;THIO-D-GLUCOSE SODIUM SALT;1-THIO-D-GLUCOSE SODIUM SALT;1-thio-alpha-d-glucopyranosmonosodiumsalt;1-THIO-D-GLUCOSE SOIUM SALT;beta-D-Thioglucose;1-Thio-D-glucose sod
• CAS NO: 62778-20-5
• Molecular Formula: C₆H₁₁O₅S*Na
• Molecular Weight: 218.2
• Mol File: 62778-20-5.mol
• Article Data: 5

Chemical Properties

• Melting Point: 170 °C
• Appearance: /
• CAS DataBase Reference: 1-THIO-D-GLUCOSE SODIUM SALT(CAS DataBase Reference)
• NIST Chemistry Reference: 1-THIO-D-GLUCOSE SODIUM SALT(62778-20-5)
• EPA Substance Registry System: 1-THIO-D-GLUCOSE SODIUM SALT(62778-20-5)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 62778-20-5(Hazardous Substances Data)

Usage

Properties

Chemical compound
Thiol derivative of D-glucose
Sodium salt form
Used as a substrate for enzyme reactions
Used in the synthesis of pharmaceutical compounds
Used as a reagent in chemical reactions
Potential applications in the development of diagnostic tools

Specific content

Used in various biochemical and pharmaceutical applications
Often used in laboratory research
Particularly used for reactions involving glycosidase enzymes
Plays a critical role in biochemical and pharmaceutical research and development

InChI:InChI=1/C6H12O5S.Na/c7-1-2-3(8)4(9)5(10)6(12)11-2;/h2-10,12H,1H2;/q;+1/p-1/t2-,3-,4+,5-,6u;/m1./s1/rC6H11NaO5S/c7-13-6-5(11)4(10)3(9)2(1-8)12-6/h2-6,8-11H,1H2/t2-,3-,4+,5-,6u/m1/s1

Upstream product

• 62860-10-0 2,3,4,6-tetra-O-acetyl-1-S-acetyl-1-thio-α-D-glucopyranoside 
• 6806-56-0 O²,O³,O⁴,O⁶,S-Pentaacetyl-1-thio-β-D-glucopyranose 
• 4451-36-9 2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl chloride 
• 604-69-3 β-D-glucose pentaacetate 

Downstream Products

• 68778-86-9 1-thio-α,β-trehalose 
• 17317-98-5 1-thio-α,α-trehalose 
• 108392-13-8 D-glycopyranosyl β-D-thioglucopyranoside 
• 130370-38-6 (5R,5aR,8aR,9S)-5-(4-Hydroxy-3,5-dimethoxy-phenyl)-9-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-ylsulfanyl)-5,8,8a,9-tetrahydro-5aH-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6-one 
• 81905-39-7 methyl 2,3,6-tri-O-benzoyl-4-S-(2,3,4,6-tetra-O-acetyl-α-D-glycopyranosyl)-4-thio-α-D-glucopyranoside 
• 68667-09-4 methyl 4-S-(α-D-glucopyranosyl)-4-thio-α-D-glucopyranoside 
• 93677-34-0 o-nitrophenyl 4-thio-α-maltoside 
• 93677-35-1 p-nitrophenyl 4-thio-α-maltoside 
• 93677-25-9 o-nitrophenyl 2,3,6-tri-O-acetyl-4-S-(2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl)-4-thio-α-D-glucopyranoside 
• 93677-26-0 p-nitrophenyl 2,3,6-tri-O-acetyl-4-S-(2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl)-4-thio-α-D-glucopyranoside 
• 93697-59-7 o-nitrophenyl 2,3,6-tri-O-benzoyl-4-S-(2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl)-4-thio-α-D-glucopyranoside 
• 93677-24-8 p-nitrophenyl 2,3,6-tri-O-benzoyl-4-S-(2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl)-4-thio-α-D-glucopyranoside 
• 130370-31-9 (5R,5aR,8aR,9S)-9-((2R,4aR,6S,7R,8R,8aS)-7,8-Dihydroxy-2-methyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-ylsulfanyl)-5-(4-hydroxy-3,5-dimethoxy-phenyl)-5,8,8a,9-tetrahydro-5aH-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6-one 
• 130370-33-1 (5R,5aR,8aR,9S)-9-((2R,4aR,6S,7R,8R,8aS)-7,8-Dihydroxy-2-methyl-hexahydro-pyrano[3,2-d][1,3]dioxine-6-sulfonyl)-5-(4-hydroxy-3,5-dimethoxy-phenyl)-5,8,8a,9-tetrahydro-5aH-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6-one 

Relevant articles and documents

BRANCHED THIOCYCLOMALTO-OLIGOSACCHARIDES: SYNTHESIS AND PROPERTIES OF 6-S-α- AND 6-S-β-D-GLUCOPYRANOSYL-6-THIOCYCLOMALTOHEPTAOSE

6-S-α- (2) and 6-S-β-D-glucopyranosyl-6-thiocyclomaltoheptaose (3) have been prepared by treatment of 6-O-p-tolylsulphonylcyclomaltoheptaose (1) with the sodium salts of 1-thio-α- and -β-D-glucopyranose, respectively, in 1,3-dimethyl-2-oxohexahydropyrimid

Inclusion and solubilization properties of 6-S-glycosyl-6-thio derivatives of β-cyclodextrin

The synthesis and physico-chemical properties of branched β-cyclodextrins substituted by one or seven thioglycoside units at the primary hydroxy side are described.The solubilities in water of these compounds are strongly increased compared with the paren

Stereoselective Thioglycoside Syntheses. Part 4. A New Approach to 1,4-linked 1-Thio-disaccharides and a Synthesis of Thiomaltose

Two approaches are devised for the preparation of thiomaltose (16).Condensation between the sodium salt of 1-thio-α-D-glucopyranose (3) and methyl 2,3,6-tri-O-benzoyl-4-O-trifluoromethylsulphonyl-α-D-galactopyranoside (5) in hexamethylphosphoramide, leads to the methyl α-thiomaltoside derivative (6).On the other hand, the displacement of the C-4 trifluoromethanesulphonate of 1,6-anhydro-D-galactopyranose diacetate (13) by the sodium salt (3) gave the 1,6-anhydro-thio-disaccharide (14).The precursor of (13), 2,3-di-O-acetyl-1,6-anhydro-β-D-galactopyranose (12) was obtained in near quantitative yield from the known 2-O-acetyl-1,6-anhydro-3,4-O-isopropylidene-β-D-galactopyranose (9) by successive hydrolysis of the acetal group, orthoester formation (11), and selective opening of this intermediate through controlled acidic hydrolysis.Acetolysis of the methyl thio-maltoside (8) or the corresponding 1,6-anhydro-thio-disaccharide (14) followed by de-O-acylation afforded 4-S-α-D-glucopyranosyl-4-thio-D-glucopyranose in excellent yields. 1,2,3,6-Tetra-O-acetyl-4-S-(2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl)-4-thio-β-D-glucopyranose (15), a useful precursor of thiomaltotriosyloligosaccharides, is also prepared from the acetolysis reaction.