628317-02-2Relevant articles and documents
Chloroperoxidase and hydrogen peroxide: An efficient system for enzymatic enantioselective sulfoxidations
Colonna,Gaggero,Casella,Carrea,Pasta
, p. 95 - 106 (1992)
High enantioselectivities were obtained in chloroperoxidase catalyzed oxidation of organic sulfides (99% ee in the case of methyl 2-pyridyl sulfide) with H2O2 in aqueous buffer solution, pH 5, at 25°C. The kinetic parameters in the oxidation of a series of sulfides both with H2O2 and tert-butyl hydroperoxide were determined and the data are consistent with enzymatic oxidation involving presumably a ternary complex. In all cases the reaction afforded the (R) sulfoxide as predominant or exclusive enantiomer.
Molecular engineering of horseradish peroxidase. Highly enantioselective sulfoxidation of aryl alkyl sulfides by the Phe-41 → leu mutant
Ozaki, Shin-Ichi,Ortiz De Montellano, Paul R.
, p. 4487 - 4488 (2007/10/02)
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