628703-61-7

Basic information

• Product Name: 5-[(AMinooxy)Methyl]-2-(1H-pyrazol-1-yl)pyridine
• Synonyms: 5-[(AMinooxy)Methyl]-2-(1H-pyrazol-1-yl)pyridine;O-((6-(1H-Pyrazol-1-yl)pyridin-3-yl)Methyl)hydroxylaMine;Pyridine, 5-[(aminooxy)methyl]-2-(1H-pyrazol-1-yl)-
• CAS NO: 628703-61-7
• Molecular Formula: C9H10N4O
• Molecular Weight: 190.2019
• EINECS: 1312995-182-4
• Mol File: 628703-61-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 395.993 °C at 760 mmHg
• Flash Point: 193.29 °C
• Appearance: /
• Density: 1.321 g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-[(AMinooxy)Methyl]-2-(1H-pyrazol-1-yl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[(AMinooxy)Methyl]-2-(1H-pyrazol-1-yl)pyridine(628703-61-7)
• EPA Substance Registry System: 5-[(AMinooxy)Methyl]-2-(1H-pyrazol-1-yl)pyridine(628703-61-7)

Safety Data

• Hazardous Substances Data: 628703-61-7(Hazardous Substances Data)

Usage

General Description

5-[(Aminooxy)Methyl]-2-(1H-pyrazol-1-yl)pyridine is a chemical compound with the molecular formula C8H8N4O. It is a pyridine derivative that contains a pyrazole ring and an aminooxy group attached to the methyl carbon. 5-[(AMinooxy)Methyl]-2-(1H-pyrazol-1-yl)pyridine is often used in organic synthesis and medicinal chemistry research. It is a versatile building block for the construction of various heterocyclic compounds and has shown potential as a drug candidate in the treatment of certain diseases. The aminooxy group in the molecule also makes it a valuable tool for bioconjugation and related applications in chemical biology.

Upstream product

• 748796-40-9 2-(6-pyrazol-1-yl-pyridin-3-ylmethoxy)-isoindole-1,3-dione 
• 896100-06-4 O-[2-(pyrazole-1-yl)pyridine-5-yl]methyl 2-butanone oxime 
• 896100-09-7 O-(2-(pyrazol-1-yl)pyridin-5-yl)methyl acetone oxime 
• 896100-11-1 2-(1-pyrazolyl)-5-pyridyl-N-methoxysuccinimide 
• 307929-00-6 O-(2-chloropyridin-5-yl)methyl acetone oxime 
• 70258-18-3 2-chloro-5-(chloromethyl)pyridine 

Relevant articles and documents

A practical synthetic method of O -(2-(Pyrazol-1-yl)pyridin-5-yl) methylhydroxylamine as a component of modithromycin

A practical synthesis of O-(2-(pyrazol-1-yl)pyridin-5-yl) methylhydroxylamine was achieved from the inexpensive raw materials, 2-chloro-5-chloromethylpyridine, pyrazole, and acetone oxime, using common reagents such as aq NaOH and sulfuric acid.

2-(PYRAZOL-1-YL)PYRIDINE DERIVATIVE

A compound having the formula (1): can be produced with efficiency by using a compound represented by the formula (2): wherein R represents a protected hydroxyl group or a group represented by the formula (3): where R1 represents an alkyl group or an aralkyl group which may be substituted; and R2 represents an alkyl.

Processes for the preparation of 6-11 bicyclic erythromycin derivatives

The present invention relates to processes and intermediates for the preparation of 6-11 bicyclic erythromycin derivatives. In particular, the present invention relates to processes and intermediates for the preparation of a compound of formula (IX-c):