628732-10-5

Basic information

• Product Name: 6-CHLORO-7-METHYL-1-INDANONE
• Synonyms: 6-CHLORO-7-METHYL-1-INDANONE;6-Chloro-7-Methyl-2,3-dihydro-1H-inden-1-one;6-chloro-7-methyl-2,3-dihydroinden-1-one
• CAS NO: 628732-10-5
• Molecular Formula: C10H9ClO
• Molecular Weight: 180.63086
• Mol File: 628732-10-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 301.4±41.0 °C(Predicted)
• Appearance: /
• Density: 1.260±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 6-CHLORO-7-METHYL-1-INDANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-CHLORO-7-METHYL-1-INDANONE(628732-10-5)
• EPA Substance Registry System: 6-CHLORO-7-METHYL-1-INDANONE(628732-10-5)

Safety Data

• Hazardous Substances Data: 628732-10-5(Hazardous Substances Data)

Usage

General Description

6-Chloro-7-methyl-1-indanone is a chemical compound with the molecular formula C10H9ClO. It is a pale yellow solid with a melting point of 62-64°C. 6-CHLORO-7-METHYL-1-INDANONE is commonly used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. It is also used as a building block for the preparation of other organic compounds. Additionally, it has been studied for its potential biological activities, including its use as an inhibitor in certain enzymatic reactions. Overall, 6-chloro-7-methyl-1-indanone has several important industrial and research applications.

Upstream product

• 7499-08-3 3-chloro-2-methylbenzoic acid 
• 74-85-1 ethene 
• 50-00-0 formaldehyd 
• 108-59-8 malonic acid dimethyl ester 

Relevant articles and documents

Rh-Catalyzed Annulation of Benzoic Acids, Formaldehyde, and Malonates via ortho-Hydroarylation to Indanones

A three-component reaction from readily available low-cost materials of benzoic acids, formaldehyde, and malonates for the preparation of indanones by rhodium catalysis is reported. The annulation is initiated by an ortho-hydroarylation of benzoic acids, and a Lewis acid is not required. The solvent has a significant influence to the reaction, and 2-substituted or nonsubstituted indanones are obtained by the change of solvent.

4-(2-Methyl-5,6,7,8-tetrahydro-quinolin-7-ylmethyl)-1,3-dihydro-imidazole-2-thione as specific alpha2B agonist and methods of using the same

The compound of the formula wherein the * indicates an asymmetric carbon, is specific to alpha2B adrenergic receptors in preference over alpha2A and alpha2C adrenergic receptors, and as such has no or only minimal cardivascular and/or sedatory activity. The compound is useful as medicament in mammals, including humans, for treatment of diseases and or alleviations of conditions which are responsive to treatment by agonists of alpha2B adrenergic receptors.