628732-11-6

Basic information

• Product Name: 4,5-Difluoroindan-1-one
• Synonyms: 4,5-Difluoro-1-indanone;4,5-Difluoroindan-1-one;4,5-difluoro-2,3-dihydroinden-1-one;4,5-Difluoro-2,3-dihydro-1H-inden-1-one;1H-Inden-1-one, 4,5-difluoro-2,3-dihydro-
• CAS NO: 628732-11-6
• Molecular Formula: C₉H₆F₂O
• Molecular Weight: 168.14
• Product Categories: Indanone & Indene
• Mol File: 628732-11-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 259.7 °C at 760 mmHg
• Flash Point: 99 °C
• Appearance: /
• Density: 1.362 g/cm³
• Vapor Pressure: 0.0128mmHg at 25°C
• Refractive Index: 1.536
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4,5-Difluoroindan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-Difluoroindan-1-one(628732-11-6)
• EPA Substance Registry System: 4,5-Difluoroindan-1-one(628732-11-6)

Safety Data

• Hazardous Substances Data: 628732-11-6(Hazardous Substances Data)

Usage

General Description

4,5-Difluoroindan-1-one is a chemical compound with the molecular formula C9H7F2O. It is an aromatic ketone that contains two fluorine atoms attached to the indan-1-one structure. 4,5-Difluoroindan-1-one is commonly used in the pharmaceutical industry as a building block for the synthesis of various pharmaceuticals and agrochemicals. It is also used in research and development as a reagent for the creation of novel chemical compounds. Additionally, 4,5-Difluoroindan-1-one has potential applications in the field of materials science, particularly in the development of advanced polymers and organic electronic materials. However, it is important to handle this compound with care, as it may have potential health and environmental risks associated with its use.

InChI:InChI=1/C9H6F2O/c10-7-3-1-5-6(9(7)11)2-4-8(5)12/h1,3H,2,4H2

Upstream product

• 412961-97-8 3-(2,3-difluorophenyl)propionoyl chloride 
• 412961-26-3 3-(2,3-difluoro-phenyl)-propionic acid 
• 79-37-8 oxalyl dichloride 
• 236746-13-7 2,3-difluorocinnamic acid 

Downstream Products

• 628732-15-0 2-(4,5-difluoro-indan-1-yl)-ethanol 

Relevant articles and documents

CHEMICAL COMPOUNDS

The use of a compound of formula (I) wherein X is (i), (ii) or (iii), formula (i),formula (ii), formula (iii) Y is O, S(O)m, NR3, CR5R6, CR5R6-CR7R8, O-CR7R

4-(substituted cycloalkylmethyl) imidazole-2-thiones, 4-(substituted cycloalkenylmethyl) imidazole-2-thiones, 4-(substituted cycloalkylmethyl) imidazol-2-ones and 4-(substituted cycloalkenylmethyl) imidazol-2-ones and related compounds

Compounds of Formula 1 where X is S and the variables have the meaning defined in the specification are specific or selective to alpha2B and/or alpha2C adrenergic receptors in preference over alpha2A adrenergic receptors, and as such have no or only minimal cardivascular and/or sedatory activity. These compounds of Formula 1 are useful as medicaments in mammals, including humans, for treatment of diseases and or alleviations of conditions which are responsive to treatment by agonists of alpha2B adrenergic receptors. Compounds of Formula 1 where X is O also have the advantageous property that they have no or only minimal cardivascular and/or sedatory activity and are useful for treating pain and other conditions with no or only minimal cardivascular and/or sedatory activity.

4-SUBSTITUTED IMIDAZOLE-2-THIONES AND IMIDAZOL- 2-ONES AS AGONISTS OF THE ALPHA- 2B AND ALPHA-2C ADRENERGIC RECEPTORS

Compounds of Formula (I): where X is S and the variables have the meaning defined in the specification are specific or selective to alpha2B and/or alpha2C adrenergic receptors in preference over alpha2A adrenergic receptors, and as such have no or only minimal cardivascular and/or sedatory activity. These compounds of Formula (I) are useful as medicaments in mammals, including humans, for treatment of diseases and or alleviations of conditions which are responsive to treatment by agonists of alpha2B adrenergic receptors. Compounds of Formula (I) where X is O also have the advantageous property that they have no or only minimal cardivascular and/or sedatory activity and are useful for treating pain and other conditions with no or only minimal cardivascular and/or sedatory activity.