628732-49-0 Usage
Description
(1S)-2,3-DIHYDRO-5-FLUORO-1H-INDENE-1-CARBOXYLIC ACID is a chiral carboxylic acid derivative of 5-fluoro-1H-indene, characterized by its (1S) configuration. (1S)-2,3-DIHYDRO-5-FLUORO-1H-INDENE-1-CARBOXYLIC ACID is a valuable building block in the pharmaceutical industry due to its structural characteristics and the presence of a fluorine substituent, which can enhance the biological activity and pharmacokinetic properties of resulting drug molecules.
Used in Pharmaceutical Industry:
(1S)-2,3-DIHYDRO-5-FLUORO-1H-INDENE-1-CARBOXYLIC ACID is used as a starting material for the synthesis of various pharmaceutical drugs. Its unique structure makes it suitable for the modification of indene-based drugs and the development of new drug candidates, contributing to the advancement of medicinal chemistry and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 628732-49-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,2,8,7,3 and 2 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 628732-49:
(8*6)+(7*2)+(6*8)+(5*7)+(4*3)+(3*2)+(2*4)+(1*9)=180
180 % 10 = 0
So 628732-49-0 is a valid CAS Registry Number.
628732-49-0Relevant articles and documents
4-SUBSTITUTED IMIDAZOLE-2-THIONES AND IMIDAZOL- 2-ONES AS AGONISTS OF THE ALPHA- 2B AND ALPHA-2C ADRENERGIC RECEPTORS
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, (2008/06/13)
Compounds of Formula (I): where X is S and the variables have the meaning defined in the specification are specific or selective to alpha2B and/or alpha2C adrenergic receptors in preference over alpha2A adrenergic receptors, and as such have no or only minimal cardivascular and/or sedatory activity. These compounds of Formula (I) are useful as medicaments in mammals, including humans, for treatment of diseases and or alleviations of conditions which are responsive to treatment by agonists of alpha2B adrenergic receptors. Compounds of Formula (I) where X is O also have the advantageous property that they have no or only minimal cardivascular and/or sedatory activity and are useful for treating pain and other conditions with no or only minimal cardivascular and/or sedatory activity.
