62882-04-6

Basic information

• Product Name: 2-p-tolyloxazole
• Synonyms: 2-p-tolyloxazole;2-(4-Methylphenyl)oxazole
• CAS NO: 62882-04-6
• Molecular Formula: C₁₀H₉NO
• Molecular Weight: 159.18456
• Mol File: 62882-04-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 261℃
• Flash Point: 103℃
• Appearance: /
• Density: 1.082
• CAS DataBase Reference: 2-p-tolyloxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-p-tolyloxazole(62882-04-6)
• EPA Substance Registry System: 2-p-tolyloxazole(62882-04-6)

Safety Data

• Hazardous Substances Data: 62882-04-6(Hazardous Substances Data)

Upstream product

• 288-42-6 oxazol 
• 624-31-7 4-tolyl iodide 
• 90252-89-4 p-tolylzinc(II) chloride 
• 201017-90-5 2-(methylthio)oxazole 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 98-59-9 p-toluenesulfonyl chloride 
• 10200-70-1 2-(4-methylphenyl)-4,5-dihydro-1,3-oxazole 
• 104-85-8 para-methylbenzonitrile 
• 106-38-7 para-bromotoluene 
• 609345-33-7 oxazol-2-ylzinc(II) chloride 

Downstream Products

• 545424-39-3 4-(1,3-oxazol-2-yl)benzaldehyde 
• 1020264-31-6 5-(Pyridine-3-yl)-2-(p-tolyl)oxazole 
• 16155-60-5 5-phenyl-2-p-tolyloxazole 
• 1020264-23-6 5-o-tolyl-2-p-tolyloxazole 
• 96907-64-1 5-(4-Chloro-phenyl)-2-p-tolyl-oxazole 
• 663215-94-9 1-[4-(2-p-tolyloxazol-5-yl)phenyl]ethanone 
• 96907-63-0 2,5-bis-(4-methylphenyl)oxazole 
• 96907-65-2 5-(4-bromophenyl)-2-(4-methylphenyl)oxazole 

Relevant articles and documents

Photoinduced Heterogeneous C?H Arylation by a Reusable Hybrid Copper Catalyst

Heterogeneous copper catalysis enabled photoinduced C?H arylations under exceedingly mild conditions at room temperature. The versatile hybrid copper catalyst provided step-economical access to arylated heteroarenes, terpenes and alkaloid natural products with various aryl halides. The hybrid copper catalyst could be reused without significant loss of catalytic efficacy. Detailed studies in terms of TEM, HRTEM and XPS analysis of the hybrid copper catalyst, among others, supported its outstanding stability and reusability.

DDQ-induced dehydrogenation of heterocycles for c-c double bond formation: Synthesis of 2-thiazoles and 2-oxazoles

Strong as an Ox: 2-Thiazoles and 2-oxazoles are formed by oxidation of 2-thiazolines and 2-oxazolines without requiring substituents at the C4 and C5 positions. DDQ plays an important role as the oxidant in this transformation and metal is unnecessary. This general procedure shows good functional group tolerance and provides a wide variety of 2-thiazoles and 2-oxazoles in moderate to excellent yields.

Nickel-catalyzed synthesis of oxazoles via C-S activation

The synthesis of 2-substituted oxazoles is achieved via nickel-catalyzed cross-coupling reaction of 2-methylthio-oxazole and various organozinc reagents. An extension of this method is demonstrated with a chemoselective, one-pot synthesis of unsymmetrical