6299-04-3

Basic information

• Product Name: N-methyl-N-(1-phenylethyl)aniline
• Synonyms: N-methyl-N-(1-phenylethyl)aniline;N-Methyl-N-phenyl-N-(1-phenylethyl)aMine
• CAS NO: 6299-04-3
• Molecular Formula: C₁₅H₁₇N
• Molecular Weight: 0
• Mol File: 6299-04-3.mol
• Article Data: 26

Chemical Properties

• Boiling Point: 320.3°C at 760 mmHg
• Flash Point: 130.4°C
• Appearance: /
• Density: 1.028g/cm³
• Vapor Pressure: 0.000321mmHg at 25°C
• Refractive Index: 1.593
• CAS DataBase Reference: N-methyl-N-(1-phenylethyl)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-methyl-N-(1-phenylethyl)aniline(6299-04-3)
• EPA Substance Registry System: N-methyl-N-(1-phenylethyl)aniline(6299-04-3)

Safety Data

• Hazardous Substances Data: 6299-04-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C15H17N/c1-13(14-9-5-3-6-10-14)16(2)15-11-7-4-8-12-15/h3-13H,1-2H3

Upstream product

• 32897-40-8 N-methyl-N-(1-phenylethenyl)aniline 
• 672-65-1 (1-chloroethyl)benzene 
• 100-61-8 N-methylaniline 
• 369-57-3 benzenediazonium tetrafluoroborate 
• 75-07-0 acetaldehyde 
• 100-42-5 styrene 
• 538-51-2 benzylidene phenylamine 
• 74-88-4 methyl iodide 
• 62-53-3 aniline 
• 4316-37-4 1,1,-diethoxy-1-phenylethane 
• 100-41-4 ethylbenzene 
• 536-74-3 phenylacetylene 
• 98-86-2 acetophenone 
• 99421-72-4 1-phenylethyl 2,2,2-trichloroacetimidate 

Downstream Products

• 100955-63-3 N-methyl-N-(1-phenyl-ethyl)-aniline-N-oxide 

Relevant articles and documents

Cleavage∕cross-coupling strategy for converting β-O-4 linkage lignin model compounds into high valued benzyl amines via dual C–O bond cleavage

Lignin is the most recalcitrant of the three components of lignocellulosic biomass. The strength and stability of the linkages have long been a great challenge for the degradation and valorization of lignin biomass to obtain bio-fuels and commercial chemicals. Up to now, the selective cleavage of C–O linkages of lignin to afford chemicals contains only C, H and O atoms. Our group has developed a cleavage/cross-coupling strategy for converting 4-O-5 linkage lignin model compounds into high value-added compounds. Herein, we present a palladium-catalyzed cleavage/cross-coupling of the β-O-4 lignin model compounds with amines via dual C–O bond cleavage for the preparation of benzyl amine compounds and phenols.

Achieving Aliphatic Amine Addition to Arylalkynes via the Lewis Acid Assisted Triazole-Gold (TA-Au) Catalyst System

Transition metal catalyzed intermolecular hydroamination of the arylalkynes with aliphatic amine is generally problematic due to the good coordination between amine and metal cation. With the combination of 1,2,3-triazole coordinated gold(I) catalyst (TA-Au) and Zn(OTf)2 cocatalyst, this challenging transformation was achieved with good to excellent yields and regioselectivity. Compared to previously reported methods, this approach offered an alternative catalyst system to achieve this fundamental chemical transformation with high efficiency and practical conditions.

Tin-Catalyzed Selective Reductive Hydroamination of Alkynes for the Synthesis of Tertiary Amines

A unique preference of tin(II) for aniline activation is disclosed. In the present work tin(II) triflate-catalyzed highly selective Markovnikov reductive hydroamination of internal as well as terminal alkynes is reported. The mechanistic study revealed the involvement of two steps in one pot wherein alkyne reduces to corresponding alkene in presence of PMHS as reducing agent followed by hydroamination of alkene. A broad range of alkynes transformed into tertiary amines with good to excellent yield. This method is equally applicable in synthesis of secondary amines.