6299-37-2 Usage
General Description
1,3,5-tris(2-chloroethyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione, also known as Tretamine, is a chemical compound used in the pharmaceutical industry as an antineoplastic agent in the treatment of various types of cancer. It works by interfering with the growth and spread of cancer cells in the body. Tretamine is a derivative of the triazine compound and is classified as an alkylating agent, which means it works by attaching alkyl groups to DNA, ultimately damaging the DNA and preventing cancer cells from growing and multiplying. It is administered intravenously and is usually used in combination with other chemotherapy drugs for the treatment of ovarian and breast cancer. Due to its potency and potential toxic effects, Tretamine is only used under the supervision of a qualified healthcare professional.
Check Digit Verification of cas no
The CAS Registry Mumber 6299-37-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,9 and 9 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 6299-37:
(6*6)+(5*2)+(4*9)+(3*9)+(2*3)+(1*7)=122
122 % 10 = 2
So 6299-37-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H12Cl3N3O3/c10-1-4-13-7(16)14(5-2-11)9(18)15(6-3-12)8(13)17/h1-6H2
6299-37-2Relevant articles and documents
Synthesis and biological evaluation of novel cyanuric acid-tethered tris-pyridinium derivatives
Derkach, Yana V.,Detusheva, Elena V.,Egorov, Mikhail P.,Frolov, Nikita A.,Minaeva, Alexandra P.,Vereshchagin, Anatoly N.
, p. 368 - 369 (2021)
Novel tris(4-alkylaminopyridin-1-ium) trichlorides with alkylcyanuric spacer were synthesized by quaternization of 4-alkylaminopyridines with tris(2-chloroethyl) cyanurate. The obtained compounds were evaluated for microbiological activity against five pathogenic bacterial strains (Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus, Acinobacter baumannii, Pseudomonas aeruginosa). The results indicate the presence of pronounced antibacterial properties in this group of compounds.
