63007-15-8

Basic information

• Product Name: trans-(4S,5S)-2-benzoyl-4-(methoxymethyl)-5-phenyl-2-oxazoline
• Synonyms: trans-(4S,5S)-2-benzoyl-4-(methoxymethyl)-5-phenyl-2-oxazoline
• CAS NO: 63007-15-8
• Molecular Weight: 295.338
• Mol File: 63007-15-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: trans-(4S,5S)-2-benzoyl-4-(methoxymethyl)-5-phenyl-2-oxazoline(CAS DataBase Reference)
• NIST Chemistry Reference: trans-(4S,5S)-2-benzoyl-4-(methoxymethyl)-5-phenyl-2-oxazoline(63007-15-8)
• EPA Substance Registry System: trans-(4S,5S)-2-benzoyl-4-(methoxymethyl)-5-phenyl-2-oxazoline(63007-15-8)

Safety Data

• Hazardous Substances Data: 63007-15-8(Hazardous Substances Data)

Upstream product

• 58635-82-8 (S,S)-2-benzyl-4-methoxymethyl-5-phenyl-2-oxazoline 

Downstream Products

• 73697-95-7 1-((4S,5S)-4-Methoxymethyl-5-phenyl-4,5-dihydro-oxazol-2-yl)-3-methyl-1-phenyl-butan-1-ol 
• 73697-99-1 ((4S,5S)-4-Methoxymethyl-5-phenyl-4,5-dihydro-oxazol-2-yl)-(4-methoxy-phenyl)-phenyl-methanol 
• 63007-16-9 1-((4S,5S)-4-Methoxymethyl-5-phenyl-4,5-dihydro-oxazol-2-yl)-1-phenyl-ethanol 
• 69766-02-5 1-((4S,5S)-4-Methoxymethyl-5-phenyl-4,5-dihydro-oxazol-2-yl)-1-phenyl-propan-1-ol 
• 73697-94-6 1-((4S,5S)-4-Methoxymethyl-5-phenyl-4,5-dihydro-oxazol-2-yl)-2-methyl-1-phenyl-propan-1-ol 
• 73697-92-4 1-((4S,5S)-4-Methoxymethyl-5-phenyl-4,5-dihydro-oxazol-2-yl)-1-phenyl-butan-1-ol 
• 73697-97-9 ((4S,5S)-4-Methoxymethyl-5-phenyl-4,5-dihydro-oxazol-2-yl)-phenyl-p-tolyl-methanol 
• 73698-01-8 ((4S,5S)-4-Methoxymethyl-5-phenyl-4,5-dihydro-oxazol-2-yl)-naphthalen-1-yl-phenyl-methanol 
• 115156-63-3 (R)-Hydroxy-naphthalen-1-yl-phenyl-acetic acid 
• 73698-08-5 (S)-Hydroxy-naphthalen-1-yl-phenyl-acetic acid 
• 64471-38-1 (S)-Hydroxy-phenyl-thiophen-2-yl-acetic acid 
• 320348-18-3 (+)-hydroxy(phenyl)2-thienylacetic acid 
• 51999-09-8 acide phenyl-2 (methyl-4 phenyl)-2 hydroxy-2 ethanoique 
• 52166-05-9 acide phenyl-2 (methyl-4 phenyl)-2 hydroxy-2 ethanoique 

Relevant articles and documents

Asymmetric Addition of Organometallics to Chiral Ketooxazolines. Preparation of Enantiomerically Enriched α-Hydroxy Acids

Addition of Grignard and organolithium reagents to chiral α-ketooxazolines results in α-substituted α-hydroxyoxazoline derivatives which on hydrolytic removal of the chiral auxiliary groups give rise to α-substituted α-hydroxy acids in 30-87 percent enantiomeric excess (ee).Studies on the various parameters (solvents, temperature, substituents) were undertaken to reach optimum asymmetric induction.