630103-11-6Relevant articles and documents
Synthesis, Activity, and Molecular Modeling Studies of Novel Human Aldose Reductase Inhibitors Based on a Marine Natural Product
De La Fuente, Jesús ángel,Manzanaro, Sonia,Martín, María Jesús,De Quesada, Teresa G.,Reymundo, Isabel,Luengo, Santos M.,Gago, Federico
, p. 5208 - 5221 (2003)
Aldose reductase (ALR2) has been implicated in the etiology of diabetic complications, including blindness. Because of the limited number of currently available drugs for the prevention of these long-term complications, the discovery of new ALR2 inhibitor