630116-52-8

Basic information

• Product Name: 4-(2-METHYLPHENYL)PIPERIDINE
• Synonyms: 4-(2-METHYLPHENYL)PIPERIDINE;OTAVA-BB 1287664;4-(o-Tolyl)
• CAS NO: 630116-52-8
• Molecular Formula: C₁₂H₁₇N
• Molecular Weight: 175.27008
• Mol File: 630116-52-8.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(2-METHYLPHENYL)PIPERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-METHYLPHENYL)PIPERIDINE(630116-52-8)
• EPA Substance Registry System: 4-(2-METHYLPHENYL)PIPERIDINE(630116-52-8)

Safety Data

• Hazardous Substances Data: 630116-52-8(Hazardous Substances Data)

Usage

General Description

4-(2-Methylphenyl)piperidine is a chemical compound with the molecular formula C13H19N. It is a piperidine derivative with a methylphenyl group attached to the fourth position on the piperidine ring. 4-(2-METHYLPHENYL)PIPERIDINE has been studied for its potential pharmacological properties, including its potential use as a psychoactive drug or as a precursor for the synthesis of other organic compounds. It may also have potential applications in medicinal chemistry and drug development. However,

Upstream product

• 651053-90-6 tert-butyl 4-(2'-methylphenyl)piperidine-1-carboxylate 
• 694-05-3 1,2,3,6-tetrahydropyridine 
• 108-88-3 toluene 
• 651053-87-1 phenyl 4-(2'-methylphenyl)piperidine-1-carboxylate 
• 821768-11-0 1,2,3,6-tetrahydro-4-(2-methylphenyl)-1-(phenylmethyl)-pyridine 
• 885982-06-9 4-(2-methylphenyl)piperidine-2,6-dione 
• 59577-81-0 3-(2-methylphenyl)pentan-1,5-dioic acid 
• 64380-54-7 2-(2-methylphenyl)-1,3-dioxolane 
• 34824-58-3 2-(2-bromophenyl)-1,3-dioxolan 
• 24393-41-7 ethyl 2-cyano-3-(2-methylphenyl)acrylate 
• 529-20-4 2-methylphenyl aldehyde 
• 6630-33-7 ortho-bromobenzaldehyde 
• 83674-75-3 1-benzyl-4-o-tolylpiperidin-4-ol 
• 3612-20-2 1-phenylmethyl-4-piperidone 

Downstream Products

• 911856-38-7 (+/-)-2-(4-(2-methylphenyl)piperidino)cyclohexanol 
• 82212-02-0 4-(2-methylphenyl)piperidine hydrogen chloride salt 
• 1189532-96-4 8-hydroxy-2-(4-o-tolylpiperidin-1-yl)naphthalene-1,4-dione 
• 1623467-77-5 3,3-diethyl-5-(4-o-tolyl-piperazin-1-ylmethyl)-dihydrofuran-2-one 

Relevant articles and documents

20-HETE FORMATION INHIBITORS

This disclosure provides novel heterocyclic compounds and methods for inhibiting the enzyme CYP4. Further disclosed methods include: a method of inhibiting the biosynthesis of 20-hydroxyeicosatetraenoic acid (20-HETE) in a subject in need thereof and a method of producing neuroprotection and decreased brain damage by preventing cerebral microvascular blood flow impairment and anti-oxidant mechanisms in a subject experiencing or having experienced an ischemic event.

(4-PHENYL-PIPERIDIN-1-YL)-[5-1H-PYRAZOL-4YL)-THIOPHEN-3-YL]-METHANONE COMPOUNDS AND THEIR USE

The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain (4-phenyl-piperidin-1-yl)- [5-(1 H-pyrazol-4-yl)-thiophen-3-yl]-methanone compounds that, inter alia, inhibit 11 β-hydroxysteroid dehydrogenase type 1 (11 β-HSD1 ). The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit 1 1 β-hydroxysteroid dehydrogenase type 1; to treat disorders that are ameliorated by the inhibition of 11 β-hydroxysteroid dehydrogenase type 1; to treat the metabolic syndrome, which includes disorders such as type 2 diabetes and obesity, and associated disorders including insulin resistance, hypertension, lipid disorders and cardiovascular disorders such as ischaemic (coronary) heart disease; to treat CNS disorders such as mild cognitive impairment and early dementia, including Alzheimer's disease; etc.

CYCLOALKANOPYRIDINE DERIVATIVE

Provided are cycloalkanopyridine derivatives of formula [I]: [wherein the symbols are the same as those stated in the description]. The compounds act as a nociceptin receptor antagonist, and are useful as medicines for diseases associated with a nociceptin receptor, for example, as a reliever against tolerance to a narcotic analgesic; a reliever against dependence on or addiction to a narcotic analgesic; an analgesic enhancer; an antiobesitic or appetite suppressor; a treating or prophylactic agent for cognitive impairment and dementia/amnesia; an agent for treating developmental cognitive abnormality; a remedy for schizophrenia; an agent for treating neurodegenerative diseases; an anti-depressant or treating agent for affective disorder; a treating or prophylactic agent for diabetes insipidus; a treating or prophylactic agent for polyuria; or a remedy for hypotension.