630118-64-8 Usage
Description
A-412997, also known as A-412997 Dihydrochloride, is a selective agonist of the dopamine D4 receptor. It plays a crucial role in various cognitive and motor functions and has potential therapeutic applications in treating psychiatric and neurological disorders.
Uses
Used in Pharmaceutical Industry:
A-412997 is used as a selective agonist for the dopamine D4 receptor for its potential therapeutic effects in treating psychiatric and neurological disorders. Its ability to modulate dopamine receptor activity makes it a promising candidate for the development of new treatments for conditions such as schizophrenia, bipolar disorder, and Parkinson's disease.
Used in Research Applications:
A-412997 is used as a research tool to study the role of dopamine D4 receptors in cognitive, memory, learning, and motor control processes. It helps researchers understand the underlying mechanisms of these receptors and their involvement in various physiological and pathological conditions.
Used in Drug Development:
A-412997 serves as a lead compound in the development of new drugs targeting the dopamine D4 receptor. Its selective agonist properties make it a valuable starting point for designing and optimizing novel therapeutic agents with improved efficacy and safety profiles for the treatment of psychiatric and neurological disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 630118-64-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,3,0,1,1 and 8 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 630118-64:
(8*6)+(7*3)+(6*0)+(5*1)+(4*1)+(3*8)+(2*6)+(1*4)=118
118 % 10 = 8
So 630118-64-8 is a valid CAS Registry Number.
630118-64-8Relevant articles and documents
Dopamine D4 Receptor-Selective Compounds Reveal Structure-Activity Relationships that Engender Agonist Efficacy
Keck, Thomas M.,Free, R. Benjamin,Day, Marilyn M.,Brown, Sonvia L.,Maddaluna, Michele S.,Fountain, Griffin,Cooper, Charles,Fallon, Brooke,Holmes, Matthew,Stang, Christopher T.,Burkhardt, Russell,Bonifazi, Alessandro,Ellenberger, Michael P.,Newman, Amy H.,Sibley, David R.,Wu, Chun,Boateng, Comfort A.
, p. 3722 - 3740 (2019/04/16)
The dopamine D4 receptor (D4R) plays important roles in cognition, attention, and decision making. Novel D4R-selective ligands have promise in medication development for neuropsychiatric conditions, including Alzheimer's d
Acetamides and benzamides that are useful in treating sexual dysfunction
-
, (2008/06/13)
The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction.
