630121-83-4

Basic information

• Product Name: 3-(2-Thiazolyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester
• Synonyms: 3-(2-Thiazolyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester;3-(2-Thiazolyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester
• CAS NO: 630121-83-4
• Molecular Formula: C₁₃H₂₀N₂O₂S
• Molecular Weight: 268.379
• Mol File: 630121-83-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 368.8±35.0 °C(Predicted)
• Appearance: /
• Density: 1.158±0.06 g/cm3(Predicted)
• PKA: 3.07±0.10(Predicted)
• CAS DataBase Reference: 3-(2-Thiazolyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-Thiazolyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester(630121-83-4)
• EPA Substance Registry System: 3-(2-Thiazolyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester(630121-83-4)

Safety Data

• Hazardous Substances Data: 630121-83-4(Hazardous Substances Data)

Upstream product

• 877168-33-7 5-(thiazol-2-yl)-3,4-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester 
• 98977-36-7 3-oxo-piperidine-1-carboxylic acid tert-butyl ester 
• 149108-74-7 5-trifluoromethanesulfonyloxy-3,4-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester 
• 630121-82-3 tert-butyl 5-(1,3-thiazol-2-yl)-3,6-dihydropyridine-1(2H)-carboxylate 

Downstream Products

• 630121-84-5 3-(thiazol-2-yl)piperidine 
• 861965-65-3 1-(4-fluorophenyl)-3-[3-(1,3-thiazol-2-yl)piperidin-1-yl]propan-1-one 

Relevant articles and documents

Synthesis and evaluation of 3-aryl piperidine analogs as potent and efficacious dopamine D4 receptor agonists

A series of 3-aryl piperidine analogs with 2-piperidinoalkylamino or 2-piperidinoalkyloxy fused bicyclic rings were prepared and found to be potent and efficacious human dopamine D4 agonists. The synthesis and structure-activity relationship (SAR) studies that led to the identification of these compounds are discussed.

Acetamides and benzamides that are useful in treating sexual dysfunction

The present invention relates to the use of compounds of formula (I) for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction.