63037-63-8

Basic information

• Product Name: 1-Bromo-2-iodo-4-nitrobenzene
• Synonyms: 1-Bromo-2-iodo-4-nitrobenzene;4-Bromo-3-iodonitrobenzene
• CAS NO: 63037-63-8
• Molecular Formula: C₆H₃BrINO₂
• Molecular Weight: 327.90199
• Mol File: 63037-63-8.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 330.6°Cat760mmHg
• Flash Point: 153.8°C
• Appearance: /
• Density: 2.349g/cm³
• Vapor Pressure: 0.000316mmHg at 25°C
• Refractive Index: 1.691
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-Bromo-2-iodo-4-nitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Bromo-2-iodo-4-nitrobenzene(63037-63-8)
• EPA Substance Registry System: 1-Bromo-2-iodo-4-nitrobenzene(63037-63-8)

Safety Data

• Hazardous Substances Data: 63037-63-8(Hazardous Substances Data)

Usage

Description

1-Bromo-2-iodo-4-nitrobenzene is a halogenated aromatic compound that consists of a benzene ring with bromine and iodine atoms at the 1st and 2nd positions, respectively, and a nitro group at the 4th position. 1-Bromo-2-iodo-4-nitrobenzene is known for its unique chemical properties and reactivity, making it a valuable intermediate in various chemical reactions and synthesis processes.

Uses

Used in Organic Synthesis:
1-Bromo-2-iodo-4-nitrobenzene is used as a reactant in the iodination of deactivated aromatics with N-iodosuccinimide. This application is particularly important in the synthesis of various organic compounds, as it allows for the selective introduction of iodine atoms into the aromatic ring, which can be further modified or used as a building block for more complex molecules.
Used in Pharmaceutical Industry:
1-Bromo-2-iodo-4-nitrobenzene can be used as a key intermediate in the synthesis of pharmaceutical compounds, particularly those that require the presence of halogenated aromatic moieties. Its unique structure and reactivity make it a valuable component in the development of new drugs and therapeutic agents.
Used in Chemical Research:
As a halogenated aromatic compound, 1-Bromo-2-iodo-4-nitrobenzene is also used in chemical research to study the reactivity and properties of halogens in aromatic systems. This can provide valuable insights into the mechanisms of various chemical reactions and help in the development of new synthetic methods and strategies.

InChI:InChI=1/C6H3BrINO2/c7-5-2-1-4(9(10)11)3-6(5)8/h1-3H

Upstream product

• 10403-47-1 2-bromo 5-nitroaniline 
• 586-78-7 para-nitrophenyl bromide 

Downstream Products

• 63037-64-9 4-bromo-3-iodoaniline 
• 25165-84-8 1-ethyl-5-(4-bromo-3-iodo-phenyl)-biguanide 
• 489409-86-1 2-bromo-5-nitro-1,1'-biphenyl 

Relevant articles and documents

Inducing axial chirality in a "Gel?nder" oligomer by length mismatch of the oligomer strands

Helical molecules are not only esthetically appealing due to their structural beauty, they also display unique physical properties as a result of their chirality.We describe herein a new approach to "Gel?nder" oligomers by interlinking two oligomer strand

Superactive iodination reagent on a base of iodine chloride and silver sulfate

After reaction of ICl and Ag2SO4 in sulfuric acid and separation of resulting AgCl a stable solution is formed, containing very active forms of electrophilic iodine. This solution has a powerful iodination ability with respect to aromatic compounds. Deactivated arenes are iodinated easily and in mild conditions by action of this new reagent in generally good yields of the iodoarenes.

Iodination of Deactivated Aromatics with N-Iodosuccinimide in Trifluoromethanesulfonic Acid (NIS-CF3SO3H) via in Situ Generated Superelectrophile Iodine(I) Trifluoromethanesulfonate

-