6304-23-0

Basic information

• Product Name: 2-(butan-2-yl)pyridine
• Synonyms: Pyridine, methylpropyl-
• CAS NO: 6304-23-0
• Molecular Formula: C₉H₁₃N
• Molecular Weight: 135.2062
• Mol File: 6304-23-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 177.3°C at 760 mmHg
• Flash Point: 37.6°C
• Density: 0.906g/cm³
• Vapor Pressure: 1.41mmHg at 25°C
• Refractive Index: 1.49
• CAS DataBase Reference: 2-(butan-2-yl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(butan-2-yl)pyridine(6304-23-0)
• EPA Substance Registry System: 2-(butan-2-yl)pyridine(6304-23-0)

Safety Data

• Hazardous Substances Data: 6304-23-0(Hazardous Substances Data)

Usage

Physical state

Clear, colorless liquid

Odor

Distinctive, sweet, nutty aroma

Usage in food industry

Flavoring agent

Usage in pharmaceuticals

Solvent in production

Usage in perfumes and cosmetics

Fragrance ingredient

Classification

Volatile organic compound (VOC)

Potential health hazards

Harmful if inhaled, ingested, or in contact with the skin

Respiratory sensitizer

Potential to cause allergic reactions in some individuals

Industrial applications

Versatile chemical with various uses, but requires careful handling due to potential health risks.

Upstream product

• 671795-46-3 sec-butylmagnesium bromide 
• 644-98-4 2-isopropylpyridine 
• 823-96-1 Trimethylboroxine 
• 1809-10-5 3-bromopentane 
• 202923-80-6 pyridin-2-yl 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonate 

Downstream Products

• 7399-50-0 2-(1-ethylpropyl)-pyridine 

Relevant articles and documents

Barbier–Negishi Coupling of Secondary Alkyl Bromides with Aryl and Alkenyl Triflates and Nonaflates

A mild and practical Barbier–Negishi coupling of secondary alkyl bromides with aryl and alkenyl triflates and nonaflates has been developed. This challenging reaction was enabled by the use of a very bulky imidazole-based phosphine ligand, which resulted in good yields as well as good chemo- and site selectivities for a broad range of substrates at room temperature and under non-aqueous conditions. This reaction was extended to primary alkyl bromides by using an analogous pyrazole-based ligand.

Palladium-catalyzed alkylation of sp2 and sp3 C-H bonds with methylboroxine and alkylboronic acids: Two distinct C-H activation pathways

Palladium-catalyzed alkylations of sp2 and sp3 C-H bonds with either methylboroxine or alkylboronic acids were developed. Ag2O or AgCO3 is used as a crucial oxidant and promoter for the transmetalation step. Ether, ester, alcohol, and alkene functional groups are tolerated. A new C-H activation pathway differing from the cyclometalation process is elucidated using methylboroxine as the coupling partner. Copyright