630410-29-6

Basic information

• Product Name: Carbamic acid, (4-methyl-3-nitrophenyl)-, 1,1-dimethylethyl ester
• CAS NO: 630410-29-6
• Molecular Formula: C12H16N2O4
• Molecular Weight: 252.27
• Mol File: 630410-29-6.mol
• Article Data: 19

Chemical Properties

• CAS DataBase Reference: Carbamic acid, (4-methyl-3-nitrophenyl)-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, (4-methyl-3-nitrophenyl)-, 1,1-dimethylethyl ester(630410-29-6)
• EPA Substance Registry System: Carbamic acid, (4-methyl-3-nitrophenyl)-, 1,1-dimethylethyl ester(630410-29-6)

Safety Data

• Hazardous Substances Data: 630410-29-6(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 119-32-4 4-Methyl-3-nitroanilin 

Downstream Products

• 872092-02-9 tert-butyl [3-(8-methoxy-4-oxoquinazolin-3(4H)-yl)-4-methylphenyl]carbamate 
• 872091-01-5 3-(5-amino-2-methylphenyl)-8-methoxyquinazolin-4(3H)-one 
• 1086422-84-5 N-(2-methyl-5-(4-(morpholinomethyl)-3-(trifluoromethyl)benzamido)phenyl)-1H-pyrrolo[2,3-b]pyridine-5-carboxamide 
• 1086423-14-4 4-(ethylamino)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-1H-pyrrolo[2,3-b]pyridine-5-carboxamide 
• 1086423-53-1 4-chloro-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)-1H-pyrrolo[2,3-b]pyridine-5-carboxamide 
• 1086423-49-5 {3-[(4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carbonyl)-amino]-4-methyl-phenyl}-carbamic acid tert-butyl ester 
• 1086423-51-9 4-methylamino-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid (5-amino-2-methyl-phenyl)-amide 
• 1086423-52-0 N-(5-amino-2-methylphenyl)-4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxamide 
• 1086423-50-8 1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid (5-amino-2-methyl-phenyl)-amide 
• 1351237-39-2 N-(5-(3-fluoro-5-(trifluoromethyl)benzamido)-2-methylphenyl)thieno[2,3-b]pyrazine-6-carboxamide 
• 1351237-31-4 N-(5-(4-methoxy-3-(trifluoromethyl)benzamido)-2-methylphenyl)thieno[2,3-b]pyrazine-6-carboxamide 
• 1351237-36-9 N-(2-methyl-5-(4-methyl-3-(trifluoromethyl)benzamido)phenyl)thieno[2,3-b]pyrazine-6-carboxamide 

Relevant articles and documents

Heterocyclic derivatives as well as pharmaceutical compositions and application thereof

The invention discloses novel heterocyclic derivatives shown in a formula I, a formula II and a formula III, pharmaceutical compositions containing the heterocyclic derivatives and application of the heterocyclic derivatives in preparation of drugs for preventing and/or treating indications related to proton pump inhibition regulation. The heterocyclic derivatives disclosed by the invention are strong in drug effect and long in half-life period, are ideal efficient proton pump inhibitors, and can be used for treating or preventing diseases or diseases needing proton pump inhibition effect regulation, such as ulcer, esophagitis, gastritis, gastroesophageal reflux, helicobacter pylori infection, gastric cancer and the like.

FUSED 1,4-DIHYDRODIOXIN DERIVATIVES AS INHIBITORS OF HEAT SHOCK TRANSCRIPTION FACTOR 1

The present invention relates to compounds of formula I wherein A1, A2 R4 and Q are as defined herein. The compounds of the present invention are inhibitors of heat shock factor 1 (HSF1). In particular, the present invention relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of these compounds, and to pharmaceutical compositions comprising them.

4-SUBSTITUTED-(3-SUBSTITUTED-1H-PYRAZOLE-5-AMINO)-PYRIMIDINE DERIVATIVES HAVING ACTIVITY OF INHIBITING PROTEIN KINASE AND USE THEREOF

Provided are derivatives substituted by urea associated with 4-substituted-(3-substituted-1H-pyrazole-5-amino)-pyrimidine-2-amino of formula (I), wherein these compounds may selectively regulate or inhibit an information transmission process controlled by