63071-71-6

Basic information

• Product Name: 1H-Iodole-2-carbothioamide
• Synonyms: 1H-Iodole-2-carbothioamide;1H-indole-2-carbothioamide
• CAS NO: 63071-71-6
• Molecular Formula: C9H8N2S
• Molecular Weight: 176.23822
• Mol File: 63071-71-6.mol
• Article Data: 3

Chemical Properties

• Melting Point: 212-214°
• Boiling Point: 399°C at 760 mmHg
• Flash Point: 195.1°C
• Appearance: /
• Density: 1.372g/cm³
• Vapor Pressure: 1.41E-06mmHg at 25°C
• Refractive Index: 1.796
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: 1H-Iodole-2-carbothioamide(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Iodole-2-carbothioamide(63071-71-6)
• EPA Substance Registry System: 1H-Iodole-2-carbothioamide(63071-71-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 63071-71-6(Hazardous Substances Data)

Usage

General Description

1H-Iodole-2-carbothioamide is a chemical compound with the molecular formula C4H4IN2S. It is an organoiodine compound that contains a thioamide functional group. This chemical has potential applications in pharmaceutical research, as thioamides are known to exhibit diverse biological activities. Additionally, the presence of the iodine atom in the compound can potentially contribute to its reactivity and properties. Further research and study of 1H-Iodole-2-carbothioamide may reveal its potential uses in medicinal chemistry or other fields.

InChI:InChI=1/C9H8N2S/c10-9(12)8-5-6-3-1-2-4-7(6)11-8/h1-5,11H,(H2,10,12)

Upstream product

• 36193-65-4 1H-indole-2-carbonitrile 
• 1670-84-4 1H-indole-2-carboxamide 
• 58881-45-1 Indole-2-carbonyl chloride 
• 1477-50-5 Indole-2-carboxylic acid 

Downstream Products

• 111141-58-3 indole-2-carbonimidic acid-(N'-phenyl-hydrazide) 

Relevant articles and documents

A novel thiazole heterocyclic compound and its preparation method and application

The invention relates to a thiazole heterocyclic compound as well as a preparation method and application thereof. The invention discloses the thiazole heterocyclic compound shown by the general formula III in the specification, wherein X is selected from hydrogen, fluorine, chlorine, bromine, methyl, methoxy, cyano, isopropoxy and nitro; and R is selected from hydrogen and methyl. According to the invention, thiazole heterocyclic compound shown by the general formula III is subjected to lead optimization as well as measurement of antibacterial activity and plant virus resistance induction activity and research of mixing with the existing commodity preparations; and the compound can be applied to the prevention and control of the plant diseases in the fields of agriculture, forestry, gardening and hygiene and/or the prevention and control of plant pests.

Synthesis and in-vitro anticancer activity of 3,5-bis(indolyl)-1,2,4- thiadiazoles

A series of 3,5-bis(indolyl)-1,2,4-thiadiazoles were synthesized and evaluated for their cytotoxicity against selected human cancer cell lines. The reaction of indole-3-thiocarboxamide 3 with iodobenzene diacetate underwent oxidative dimerization to give 3,5-bis(indolyl)-1,2,4-thiadiazoles 4a-n. Among the synthesized bis(indoly)-1,2,4-thiadiazoles, the compound 4h with 4-chlorobenzyl and methoxy substituents showed the most potent activity.