6311-22-4

Basic information

• Product Name: 9-hydroxy-9-methylfluorene
• Synonyms: 9-hydroxy-9-methylfluorene;9-Methyl-9H-fluoren-9-ol
• CAS NO: 6311-22-4
• Molecular Formula: C₁₄H₁₂O
• Molecular Weight: 196.24
• Mol File: 6311-22-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 175.0 to 179.0 °C
• Boiling Point: 360.3°C at 760 mmHg
• Flash Point: 133.1°C
• Appearance: /
• Density: 1.198g/cm³
• Vapor Pressure: 8.04E-06mmHg at 25°C
• Refractive Index: 1.653
• Solubility: soluble in Methanol
• PKA: 13.40±0.20(Predicted)
• CAS DataBase Reference: 9-hydroxy-9-methylfluorene(CAS DataBase Reference)
• NIST Chemistry Reference: 9-hydroxy-9-methylfluorene(6311-22-4)
• EPA Substance Registry System: 9-hydroxy-9-methylfluorene(6311-22-4)

Safety Data

• Hazardous Substances Data: 6311-22-4(Hazardous Substances Data)

Usage

General Description

9-hydroxy-9-methylfluorene, also known as 9-methyl-9-fluorenol, is a polycyclic aromatic hydrocarbon compound with a hydroxyl group and a methyl group attached to a fluorene ring. It is commonly used as a reactant in organic synthesis for the production of various pharmaceuticals, agrochemicals, and dyes. 9-hydroxy-9-methylfluorene has also shown potential in anti-inflammatory and antioxidant activities. Additionally, it has been studied for its carcinogenic and mutagenic properties, raising concerns about its potential health risks with prolonged exposure. Overall, 9-hydroxy-9-methylfluorene is a versatile chemical with various industrial and research applications, but its potential health and environmental impacts warrant careful handling and regulation.

InChI:InChI=1/C14H12O/c1-14(15)12-8-4-2-6-10(12)11-7-3-5-9-13(11)14/h2-9,15H,1H3

Upstream product

• 19126-15-9 9-methoxyfluorene 
• 486-25-9 9-fluorenone 
• 2523-37-7 9-methylfluorene 

Downstream Products

• 2523-37-7 9-methylfluorene 
• 72853-56-6 Naphtho<2,3-b>fluoranthene-8,13-dione 
• 5542-59-6 1,1,5,5-Bis-biphenylen-3-phenyl-pentadien-(1,4) 
• 39194-34-8 9-methyl-9-fluorenyl methyl ether 
• 4425-82-5 9-methylene-fluorene 
• 188541-54-0 9-chloro-9-methyl-9H-fluorene 
• 64666-57-5 9-methyl-9-fluorenyl 3,5-dinitrobenzoate 
• 4569-45-3 9,9-dimethyl-9H-fluorene 
• 133295-76-8 2-hydroxy-5-methyl-3-(9-methyl-9H-fluoren-9-yl)benzaldehyde 
• 1285695-14-8 [(13C)]-9-methyl-9H-fluorene-9-carboxylic acid 
• 1072315-89-9 9-methylfluorene-9-([⁽¹³⁾C]-carbonyl) chloride 
• 486-25-9 9-fluorenone 
• 15300-82-0 9,9'-dimethyl-9,9'-bifluorene 
• 82102-37-2 9-methyl-9H-fluorene-9-carbonyl chloride 

Relevant articles and documents

Photooxidation of aryl alkanes by a decatungstate/triethylsilane system in the presence of molecular oxygen

Decatungstate photocatalyzes the oxidation of aryl alkanes to the corresponding tertiary hydroperoxides and alcohols, in the presence of molecular oxygen. The addition of triethylsilane to the reaction mixture substantially increases the proportion of hydroperoxide formed.

REACTIVITY OF CARBANIONS. XXIII. WITTIG REARRANGEMENT OF 9-FLUORENOL ETHERS UNDER THE CONDITIONS OF PHASE-TRANSFER CATALYSIS

The Wittig rearrangement of the phenyl, methyl, benzyl, and allyl ethers of 9-fluorenol was investigated under the conditions of phase-transfer catalysis in a system consisting of a solid powdered base and an organic phase.With the exception of the phenyl ether, which does not enter into the reaction, the rearrangement of all the ethers takes place by a dissociation-recombination mechanism with the formation of the fluorenone-migrating group carbanion pair as intermediate.The migratory aptitude increases in the order methyl benzyl allyl.The orders of effectiveness were established for the bases, phase transfer catalysts, and solvent in the Wittig rearrangement.