6312-20-5

Basic information

• Product Name: 1-phenyl-3-(pyridin-4-yl)propane-1,3-dione
• Synonyms: 1-phenyl-3-(4-pyridinyl)-1,3-propanedione
• CAS NO: 6312-20-5
• Molecular Formula: C₁₄H₁₁NO₂
• Molecular Weight: 225.2426
• Mol File: 6312-20-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 420°C at 760 mmHg
• Flash Point: 209.3°C
• Density: 1.184g/cm³
• Vapor Pressure: 2.92E-07mmHg at 25°C
• Refractive Index: 1.587
• CAS DataBase Reference: 1-phenyl-3-(pyridin-4-yl)propane-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-phenyl-3-(pyridin-4-yl)propane-1,3-dione(6312-20-5)
• EPA Substance Registry System: 1-phenyl-3-(pyridin-4-yl)propane-1,3-dione(6312-20-5)

Safety Data

• Hazardous Substances Data: 6312-20-5(Hazardous Substances Data)

Usage

Chemical class

Chalcones

Physical form

Yellow crystalline solid

Known for

Potential biological activities, including anti-inflammatory, anti-cancer, and antioxidant properties

Studied for

Potential in treating various diseases and conditions

Promising results

In preclinical studies

Molecular structure

A phenyl group attached to a pyridin-4-yl group through a propanedione linker

Contribution to biological activities

Unique structure of the compound

Field of interest

Medicinal chemistry and pharmaceutical research

Upstream product

• 2459-09-8 4-pyridinecarboxylic acid, methyl ester 
• 98-86-2 acetophenone 
• 55-22-1 pyridine-4-carboxylic acid 
• 1570-45-2 isonicotinic acid ethylester 
• 14254-57-0 4-(chlorocarbonyl)pyridine 

Downstream Products

• 85903-27-1 4-(5-phenylisoxazol-3-yl)pyridine 
• 85903-35-1 4-(3-phenylisoxazol-5-yl)pyridine 
• 19959-79-6 3-(4-pyridyl)-5-phenyl-1H-pyrazole 

Relevant articles and documents

Synthesis of 1,3-Diketones and β-Keto Thioesters via Soft Enolization

Ketones and thioesters undergo soft enolization and acylation using crude acid chlorides on treatment with MgBr2·OEt2 and i-Pr2NEt to give 1,3-diketones and β-keto thioesters, respectively. The use of crude acid chlorides adds efficiency and cost reduction by avoiding the need to purify and/or purchase them. The process is conducted in a direct fashion that does not require prior enolate formation, further enhancing its efficiency and making it very easy to carry out. The method is suitable for large scale applications. ?

Light-emitting organic metal silver compound with binary emission as well as preparation and application thereof

The invention relates to a series of silver halogen series compounds with a one-dimensional chain-shaped structure. A chemical formula is [Ag2LX2]n or [Ag2X2L]n, wherein n is a non-zero natural number; X is selected from halogen atoms including Cl, Br, I

Interaction of copper(II) with ditopic pyridyl-β-diketone ligands: Dimeric, framework, and metallogel structures

The interaction of Cu(II) with three β-diketone ligands of type R 1C(O)CH2C(O)R2 (where R1 = 2-, 3-, or 4-pyridyl and R2 = C6H5, respectively), HL1-HL3, alo