63141-10-6

Basic information

• Product Name: 1-Fluorocyclopropyl Methyl ketone
• Synonyms: 1-(1-Fluorocyclopropyl)ethanone;1-Fluorocyclopropyl Methyl ketone;1-Fluorocyclopropyl Methyl Ketone(WX625133)
• CAS NO: 63141-10-6
• Molecular Formula: C₅H₇FO
• Molecular Weight: 102.1068832
• Mol File: 63141-10-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 93.8±23.0 °C(Predicted)
• Appearance: /
• Density: 1.07±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 1-Fluorocyclopropyl Methyl ketone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Fluorocyclopropyl Methyl ketone(63141-10-6)
• EPA Substance Registry System: 1-Fluorocyclopropyl Methyl ketone(63141-10-6)

Safety Data

• Hazardous Substances Data: 63141-10-6(Hazardous Substances Data)

Usage

Physical state

Colorless liquid

Odor

Distinctive pungent odor

Usage

Intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds

Application

Building block in the production of various functional materials

Handling

Requires caution and care in laboratory and industrial settings due to its reactive nature

Unique property

Presence of the fluorine atom in the molecule

Value

Valuable in the field of organic chemistry due to the fluorine atom's unique properties

Upstream product

• 517-23-7 3-acetyl-2-oxo-4,5-dihydrofuran 
• 2986-00-7 3-acetyl-3-chlorodihydrofuran-2(3H)-one 
• 63141-03-7 3-acetyl-3-fluorodihydrofuran-2(3H)-one 
• 63141-07-1 3-fluoro-5-chloro-2-pentanone 
• 63141-04-8 3-fluoro-5-bromo-2-pentanone 

Downstream Products

• 137081-41-5 1-fluoro-cyclopropane-1-carboxylic acid 

Relevant articles and documents

Synthetic method of 1-halo-1-acetyl cyclopropane

The invention discloses a synthetic method of 1-halo-1-acetyl cyclopropane. The synthetic method comprises the step of preparing a 1-halo-1-acetyl cyclopropane compound by taking 3,5-dihalo-pentanoneas a raw material and taking benzyl trimethyl ammonium chloride as a phase transfer catalyst under the action of alkali. The method disclosed by the invention is simple to operate, quick to react andhigh in yield, and solves the problem of quickly and efficiently synthesizing the 1-halo-1-acetyl cyclopropane compound. The synthetic method disclosed by the invention is primarily used for synthesizing organic molecules containing cyclopropane structural units.

Process for preparing 1-fluorocyclopropyl methyl ketone

A new process for the preparation of 1-fluorocyclopropyl methyl ketone of the formula STR1 which process comprises a) in a first step, reacting 2-acetyl-2-chloro-4-butanolide of the formula STR2 with an addition product of triethylamine and hydrogen fluoride of the formula in which n represents the numbers 1, 2 or 3, in the presence of a diluent at a temperature between 20° C. and 120° C. and b) in a second step, reacting the resulting 2-acetyl-2-fluoro-4-butanolide of the formula STR3 with a nucleophilic agent in the presence of a diluent at a temperature between 50° C. and 200° C. New halogenoketones of the formula STR4 in which Hal represents chlorine or bromine.