6318-23-6

Basic information

• Product Name: -D-Galactopyranosylamine
• Synonyms: -D-Galactopyranosylamine
• CAS NO: 6318-23-6
• Molecular Formula: C₆H₁₃NO₅
• Molecular Weight: 179.17
• Product Categories: Carbohydrates & Derivatives
• Mol File: 6318-23-6.mol
• Article Data: 11

Chemical Properties

• Melting Point: 128-133°C
• Boiling Point: 416.4±45.0 °C(Predicted)
• Appearance: /
• Density: 1.563±0.06 g/cm3(Predicted)
• Storage Temp.: -20°C Freezer
• Solubility: Methanol, Water
• PKA: 13.19±0.70(Predicted)
• CAS DataBase Reference: -D-Galactopyranosylamine(CAS DataBase Reference)
• NIST Chemistry Reference: -D-Galactopyranosylamine(6318-23-6)
• EPA Substance Registry System: -D-Galactopyranosylamine(6318-23-6)

Safety Data

• Hazardous Substances Data: 6318-23-6(Hazardous Substances Data)

Usage

Description

-D-Galactopyranosylamine, with the CAS number 6318-23-6, is a white crystalline solid that serves as a valuable compound in the realm of organic synthesis. Its unique chemical structure and properties make it a versatile building block for the creation of various complex organic molecules.

Uses

Used in Pharmaceutical Industry:
-D-Galactopyranosylamine is used as a key intermediate for the synthesis of pharmaceutical compounds. Its ability to form complex organic molecules makes it a crucial component in the development of new drugs and therapeutic agents.
Used in Chemical Research:
-D-Galactopyranosylamine is used as a research tool in chemical laboratories for studying the properties and reactions of carbohydrates and their derivatives. This helps scientists gain a deeper understanding of the underlying chemistry and potentially discover new applications for this compound.
Used in Organic Synthesis:
-D-Galactopyranosylamine is used as a building block in organic synthesis for the creation of complex organic molecules, including those with potential applications in various industries such as pharmaceuticals, agrochemicals, and materials science.
Used in Material Science:
-D-Galactopyranosylamine is used as a component in the development of novel materials with specific properties, such as improved biocompatibility or enhanced chemical reactivity. Its unique structure allows for the creation of materials with tailored characteristics for various applications.

Upstream product

• 10257-28-0 D-Galactose 
• 59-23-4 D-Galactose 
• 3068-32-4 1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside 
• 4163-60-4 β-D-galactose peracetate 
• 13992-26-2 (2R,3S,4S,5R,6R)-2-(acetoxymethyl)-6-azidotetrahydro-2H-pyran-3,4,5-triyl triacetate 
• 67-56-1 methanol 
• 7664-41-7 ammonia 
• 35899-89-9 1-amido-1-deoxygalactopyranose 

Downstream Products

• 83306-52-9 N¹-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)succinamic acid 
• 287173-96-0 (S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-N-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yl)-succinamic acid pentafluorophenyl ester 
• 368886-89-9 (1,2-dideoxy-β-D-galactopyranoso)[1,2-d]-1,3-oxazolidine-2-thione 
• 33758-19-9 N-bromoacetyl-β-D-galactopyranosylamine 

Relevant articles and documents

A convenient approach for solution-phase synthesis of water-soluble galactoside libraries

A convenient approach for the solution-phase synthesis of water-soluble galactoside libraries through tributylphosphine promoted reaction of azido compounds with carboxylic acids is described.

Development of photoswitchable inhibitors for β-galactosidase

Azobenzenes are of particular interest as a photochromic scaffold for biological applications because of their high fatigue resistance, their large geometrical change between extended (trans) and bent (cis) isomer, and their diverse synthetic accessibility. Despite their wide-spread use, there is no reported photochromic inhibitor of the well-investigated enzyme β-galactosidase, which plays an important role for biochemistry and single molecule studies. Herein, we report the synthesis of photochromic competitive β-galactosidase inhibitors based on the molecular structure of 2-phenylethyl β-d-thiogalactoside (PETG) and 1-amino-1-deoxy-β-d-galactose (β-d-galactosylamine). The thermally highly stable PETG-based azobenzenes show excellent photochromic properties in polar solvents and moderate to high photostationary states (PSS). The optimized compound 37 is a strong competitive inhibitior of β-galactosidase from Escherichia coli and its inhibition constant (Ki) changes between 60 nM and 290 nM upon irradiation with light. Additional docking experiments supported the observed structure-activity relationship.

Experimental and computational studies of the recognition of amino acids by galactosyl-imine and -amine derivatives: An attempt to understand the lectin-carbohydrate interactions

(Chemical Equation Presented) A galactosyl-naphthyl-imine-based derivative, 1-(β-D-galactopyranosyl-1′-deoxy-1′-iminomethyl)-2- hydroxynaphthalene (GNI), and a galactosyl-naphthyl-amine-based derivative, 1-(galactopyranosyl-1′-deoxy-1′-aminomethyl)-2-hydroxynaphthalene (GNA), possessing an ONO binding core were studied for their recognition of naturally occurring amino acids using fluorescence and absorption spectroscopy, and the corresponding association constants were derived for the complexes formed. The complexes formed between GNI/GNA and amino acids were supported by electrospray ionization mass spectrometry (ESI/MS). The structures of the complexes were optimized by computational studies using density functional theory, and stabilization energies were computed for the complexes to substantiate the interactions present between GNI/GNA and amino acid. The interactions were found to be primarily hydrogen bonding in nature. These interactions are reminiscent of those present in the lectin-carbohydrate and glycosidase substrate. Thus, the carbohydrate moiety present in GNI shows high specificity toward the -COOH group of the amino acid, which may be relevant to such interactions present between the carbohydrates and the polypeptides.