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63184-61-2

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63184-61-2 Usage

General Description

3-(Bromomethyl)furan is an organic compound consisting of a furan ring with a bromomethyl group attached at the 3-position. It is a colorless liquid with a slightly sweet odor, and it is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. The bromomethyl group makes the compound a reactive alkylating agent, allowing it to undergo various chemical reactions to form new carbon-carbon and carbon-heteroatom bonds. 3-(Bromomethyl)furan is also used as a precursor in the synthesis of organic building blocks and is an important reagent in organic chemistry research and development. However, it should be handled with caution due to its toxicity and potential hazards during handling and storage.

Check Digit Verification of cas no

The CAS Registry Mumber 63184-61-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,1,8 and 4 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 63184-61:
(7*6)+(6*3)+(5*1)+(4*8)+(3*4)+(2*6)+(1*1)=122
122 % 10 = 2
So 63184-61-2 is a valid CAS Registry Number.
InChI:InChI=1/C5H5BrO/c6-3-5-1-2-7-4-5/h1-2,4H,3H2

63184-61-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-(Bromomethyl)furan

1.2 Other means of identification

Product number -
Other names 3-furanmethyl bromide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:63184-61-2 SDS

63184-61-2Relevant articles and documents

Synthesis and pharmacological characterisation of arctigenin analogues as antagonists of AMPA and kainate receptors

Butts, Craig P.,Collingridge, Graham L.,Jane, David E.,Mallah, Shahida,Molnár, Elek,Re?nik, Lisa-Maria,Thatcher, Robert J.,Willis, Christine L.

supporting information, p. 9154 - 9162 (2021/11/16)

(-)-Arctigenin and a series of new analogues have been synthesised and then tested for their potential as AMPA and kainate receptor antagonists of human homomeric GluA1 and GluK2 receptors expressed in HEK293 cells using a Ca2+ influx assay. In general, these compounds showed antagonist activity at both receptors with greater activity evident at AMPARs. Schild analysis indicates that a spirocyclic analogue 6c acts as a non-competitive antagonist. Molecular docking studies in which 6c was docked into the X-ray crystal structure of the GluA2 tetramer suggest that (-)-arctigenin and its analogues bind in the transmembrane domain in a similar manner to the known AMPA receptor non-competitive antagonists GYKI53655 and the antiepileptic drug perampanel. The arctigenin derivatives described herein may serve as novel leads for the development of drugs for the treatment of epilepsy. This journal is

Rapid stereoselective syntheses of heteroarene-fused azacycles via diastereoselective conjugate addition of heteroaryl substituted lithium amidest

Davies, Stephen G.,Fletcher, Ai M.,Holder, Katherine E.,Roberts, Paul M.,Thomson, James E.,Zimmer, David

, p. 919 - 941 (2019/08/01)

Conjugate addition of heteroaryl substituted lithium amides to a range of α,β-unsaturated esters followed by in situ enolate oxidation with (-)-(camphorsulfonyl)oxaziridine gave the corresponding α-hydroxy-β-amino esters. Subsequent Friedel-Crafts type cy

Asymmetric Dearomatization of 1-Aminonaphthalene Derivatives through C-C Bond Formation with Electron-Rich Heterocycles as Nucleophiles

Baba, Takafumi,Oka, Junko,Noguchi, Keiichi,Tanaka, Ken

, p. 4374 - 4382 (2015/07/27)

A cationic gold(I)/axially chiral biaryl bis(phosphine) complex has been employed to catalyze the asymmetric dearomatization reactions of 1-aminonaphthalene derivatives through a C-C bond-forming reaction with electron-rich heterocycles as the nucleophiles. These reactions afford pentacyclic heterocycles in good yields with moderate enantiomeric excess (ee) values. A cationic gold(I)/axially chiral biaryl bis(phosphine) complex has been employed to catalyze the asymmetric dearomatization of 1-aminonaphthalene derivatives through a C-C bond-forming reaction with electron-rich heterocycles as the nucleophiles. These reactions afford pentacyclic heterocycles in good yields with moderate enantiomeric excess (ee) values.

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