632-92-8Relevant articles and documents
Conjugated energetic salts based on 3,3′-((1E,1′E)-(2,4,6-trinitro-1,3-phenylene)bis(ethene-2,1-diyl))bis(2,4,6-trinitrophenol)
Xu, Junhui,Wei, Jianping,Li, Fangmei,Ma, Qingguo,Peng, Xinhua
, p. 5303 - 5311 (2014)
Based on a design strategy that has resulted in conjugated energetic materials, 3,3′-((1E,1′E)-(2,4,6-trinitro-1,3-phenylene)bis(ethane-2,1-diyl))bis(2,4,6-trinitrophenol) and its nitrogen-rich salts were obtained and characterized via spectral and elemental analyses. These new molecules exhibit good thermal stability (Td = 268.4-311.3 °C), especially for hydrazinium salt 4c, which is comparable to that of the benchmark HNS. Also, they exhibit low impact sensitivity (>40 J), high density (1.67-1.88 g cm-3), acceptable detonation properties (7268-8527 m s-1, 26.7-34.1 GPa) and brisance parameters (103.9-144.4). The energetic properties of the salts suggest potential applications to new energetic materials.
Formation constants in C-H hydrogen bonding. 4. Effects of cyano, nitro, and trifluoromethyl substituents in aromatic compounds
Lorand, John P.
, p. 186 - 205 (2015/02/19)
Formation constants ( Keq) have been measured using 1H NMR for H-bond complexes with HMPA in CCl 4of 35 aromatic compounds variously substituted with cyano, nitro, and trifluoromethyl groups; several compounds contained F and Cl. The three strongly polar groups enhance H-bonding significantly, usually in the order NO2 > CN > CF3; all are superior to Cl and F. 1,3,5-Trinitrobenzene fails to H-bond at all; however, TNT, its tert-butyl analog, and trinitro-m-xylene show significant Keq values. Coplanarity of nitro groups with the ring blocks approach of HMPA, probably via intramolecular H-bonds. The buttressing effect is evident in some crowded compounds.
Synthesis and biological activity of flavanone derivatives
Shi, Lei,Feng, Xiu E,Cui, Jing Rong,Fang, Lian Hua,Du, Guan Hua,Li, Qing Shan
scheme or table, p. 5466 - 5468 (2011/01/03)
A series of new flavanone derivatives of farrerol was synthesized by a convenient method. The in vitro anti-tumor activity of these compounds was evaluated against human Bel-7402, HL-60, BGC-823 and KB cell lines, the protein tyrosine kinase (PTK) inhibitor activity was also tested. Their cytoprotective activity was tested using hydrogen peroxide (H2O2)-induced injury in human umbilical vein endothelial cells. Their in vitro anti-atherosclerosis activity was tested on vascular smooth muscle cells by the MTT method using tetrandrine as a positive contrast drug. The structures of all compounds synthesized were confirmed by 1H, 13C NMR and ESI-MS. Most of the compounds exhibited good pharmacological activity and the preliminary structure-activity relationships were described.
