6322-51-6

Basic information

• Product Name: alpha-butylalanine
• Synonyms: alpha-butylalanine
• CAS NO: 6322-51-6
• Molecular Formula: C7H15NO2
• Molecular Weight: 145.2
• Mol File: 6322-51-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 243.4±23.0 °C(Predicted)
• Appearance: /
• Density: 1.019±0.06 g/cm3(Predicted)
• PKA: 2.58±0.44(Predicted)
• CAS DataBase Reference: alpha-butylalanine(CAS DataBase Reference)
• NIST Chemistry Reference: alpha-butylalanine(6322-51-6)
• EPA Substance Registry System: alpha-butylalanine(6322-51-6)

Safety Data

• Hazardous Substances Data: 6322-51-6(Hazardous Substances Data)

Upstream product

• 123-15-9 2-methylvaleraldehyde 
• 71680-52-9 ammonium cyanide 
• 6326-76-7 5-Methyl-5-n-butyl hydantoin 
• 109-65-9 1-bromo-butane 
• 91292-74-9 alanine ethyl ester-p-chlorobenzyl shiff base 
• 773837-37-9 sodium cyanide 
• 591-78-6 n-hexan-2-one 

Relevant articles and documents

Synthesis and structural studies of new analogues of PTH(1-11) containing Cα-tetra-substituted amino acids in position 8

The N-terminal 1-34 fragment of parathyroid hormone (PTH) is fully active in vitro and in vivo and it can reproduce all biological responses characteristic of the native intact PTH. Recently, analogues of PTH(1-11) fragments with helicity-enhancing substitutions have been demonstrated to yield potent analogues of PTH(1-34). The work describes the synthesis, biological activity and structure of analogues of the best modified PTH sequence H-Aib-Val-Aib-Glu-Ile-Gln-Leu-Nle-His-Gln-Har-NH2 (I). In particular, the effect of the Ala/Aib substitution at positions 1 and 3 as well as of the replacement of Nle in position 8 with d-Nle, l-(αMe)-Nle and d-(αMe)-Nle was studied. The resulting peptides were characterized structurally by CD spectroscopy, solution NMR and MD, and in vitro for activity with respect to the cognate receptor, parathyroid hormone receptor.