632333-59-6

Basic information

• Product Name: 4,6,8-trimethyl-2-phenylpyrazolo<5,4-d:2,3-a'>dipyrimidine
• Synonyms: 4,6,8-trimethyl-2-phenylpyrazolo<5,4-d:2,3-a'>dipyrimidine
• CAS NO: 632333-59-6
• Molecular Weight: 289.34
• Mol File: 632333-59-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4,6,8-trimethyl-2-phenylpyrazolo<5,4-d:2,3-a'>dipyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6,8-trimethyl-2-phenylpyrazolo<5,4-d:2,3-a'>dipyrimidine(632333-59-6)
• EPA Substance Registry System: 4,6,8-trimethyl-2-phenylpyrazolo<5,4-d:2,3-a'>dipyrimidine(632333-59-6)

Safety Data

• Hazardous Substances Data: 632333-59-6(Hazardous Substances Data)

Upstream product

• 3043-28-5 3-bromopentane-2,4-dione 
• 115073-23-9 4-Methyl-6-phenyl-1H-pyrazolo[3,4-d]pyrimidin-3-ylamine 
• 123-54-6 acetylacetone 
• 115073-23-9 3-amino-4-methyl-6-phenyl-pyrazolo[3,4-d]pyrimidine 
• 2228-12-8 6-methyl-4-phenyl-2-thioxo-1,2-dihydropyrimidine-5-carbonitrile 
• 98-88-4 benzoyl chloride 
• 35260-93-6 ethyl 2-cyano-3-ethoxybut-2-enoate 
• 618-39-3 benzamidin 
• 914074-37-6 4-chloro-6-methyl-2-phenylpyrimidine-5-carbonitrile 
• 115073-24-0 4-hydrazino-6-methyl-2-phenylpyrimidine-5-carbonitrile 
• 82114-04-3 4-hydroxy-6-methyl-2-phenylpyrimidine-5-carbonitrile 

Relevant articles and documents

Synthesis of some new 6,8-disubstituted 7,8-dihydropyrimido[2,3:4,3] pyrazolo[1,5-a]pyrimidines and 6,7,8-trisubstituted pyrimido[2,3:4,3]pyrazolo[1, 5-a]pyrimidine derivatives

Cyclization of 5-cyano-1,6-dihydro-4-methyl-2-phenyl-6-thioxopyrimidine 4 with excess of 85% hydrazine hydrate afforded the 3-amino-4-methyl-6- phenylpyrazolo[3,4-d]pyrimidine 5, which can react with appropriate Mannich base derivatives 13a-c and chalcones 27a,b to yield the corresponding 6,8-disubstituted 7,8-dihydropyrimido[2,3:4,3]pyrazolo[1,5-a]pyrimidines 15a-c and 30a,b, respectively. On the other hand, the 6,7,8-trisubstituted pyrimido[2,3:4,3]pyrazolo[1,5-a]pyrimidine derivatives 8a-g, 20a-e, 36 and 38 were obtained by treatment of compound 5 with appropriate 1,3-diketones 6a-g, 3-dimethylamino-1-(substituted)prop-2-enones 18a-e, 3-aminocrotononitrile 3, and ethoxymethylenemalononitrile 37 under acidic condition, respectively.