63240-66-4

Basic information

• Product Name: 3',4',6'-tri-O-benzyl-2'-hydroxy-4-methoxychalcone
• CAS NO: 63240-66-4
• Molecular Weight: 572.657
• Mol File: 63240-66-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3',4',6'-tri-O-benzyl-2'-hydroxy-4-methoxychalcone(CAS DataBase Reference)
• NIST Chemistry Reference: 3',4',6'-tri-O-benzyl-2'-hydroxy-4-methoxychalcone(63240-66-4)
• EPA Substance Registry System: 3',4',6'-tri-O-benzyl-2'-hydroxy-4-methoxychalcone(63240-66-4)

Safety Data

• Hazardous Substances Data: 63240-66-4(Hazardous Substances Data)

Upstream product

• 100-44-7 benzyl chloride 
• 480-66-0 2,4,6-trihydroxyacetophenone 
• 18065-05-9 1-[2,4-bis(benzyloxy)-6-hydroxyphenyl]ethanone 
• 6346-05-0 3-benzyloxy-4-methoxybenzaldehyde 

Downstream Products

• 87530-21-0 5,7,3'-trihydroxy-4'-methoxy-6,8-di-C-prenylisoflavone 
• 2284-31-3 3',5,7-trihydroxy-4'-methoxyisoflavone 

Relevant articles and documents

Synthesis of Naturally Occuring Pratensein and 6,8-Di-C-prenylpratensein

Pratensein (4a) has now been synthesized in two ways.The first route involves condensation of phloroacetophenone dibenzyl ether (1) with O-benzylisovanillin (2) and oxidative cyclization of the resulting chalcone (3) with Tl(NO3)3-MeOH followed by boiling with HCl.In the second route 2,4,6,3'-tetrahydroxy-4'-methoxydesoxybenzoin (5) is treated with DMF, CH3SO2Cl and BF3-Et2O.When pratensein is reacted with 3-hydroxy-3-methyl-1-butene in the presence of BF3-Et2O and dioxan, it gives the naturally occuring 6,8-di-C-prenylpratensein (6a).