6326-74-5 Usage
General Description
AKOS B018327 is a chemical compound with the molecular formula C25H31N3O3. It is a synthetic compound with potential use in pharmacological research and drug development. There is limited information available about its specific properties and uses, but it may have effects on the central nervous system or other biological activities. Further research is needed to fully understand its potential applications and mechanisms of action.
Check Digit Verification of cas no
The CAS Registry Mumber 6326-74-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,3,2 and 6 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 6326-74:
(6*6)+(5*3)+(4*2)+(3*6)+(2*7)+(1*4)=95
95 % 10 = 5
So 6326-74-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H11NO3S2/c1-15-8-4-3-7(5-9(8)16-2)6-10-11(14)13-12(17)18-10/h3-6H,1-2H3,(H,13,14,17)/b10-6+
6326-74-5Relevant articles and documents
Introducing broadened antibacterial activity to rhodanine derivatives targeting enoyl-acyl carrier protein reductase
Sun, Zhi-Gang,Xu, Yun-Jie,Xu, Jian-Fei,Liu, Qi-Xing,Yang, Yu-Shun,Zhu, Hai-Liang
, p. 125 - 129 (2019/03/28)
Broadened antibacterial activity was introduced to rhodanine derivatives targeting Mycobacterial tuberculosis enoyl-acyl carrier protein reductase (Mtb InhA) by recruiting feature of xacins to bring DNA Gyrase B inhibitory capability. This is significant for preventing further bacterial injections in the tuberculosis treatment. The most potent compound Cy14 suggested comparable bioactivity (IC50=3.18μM for Mtb InhA; IC50=10nM for DNA Gyrase B) with positive controls. Structure–activity relationship discussion and molecular docking model revealed the significance of rhodanine moiety and derived methoxyl on meta-position, pointing out orientations for future modification.
