6328-77-4

Basic information

• Product Name: AKOS 243-39
• Synonyms: AKOS 243-39;BENZAMIDE, N-(2,4-DIMETHYLPHENYL)-;N-(2,4-DIMETHYLPHENYL)-BENZAMIDE;2',4'-BENZOXYLIDIDE
• CAS NO: 6328-77-4
• Molecular Formula: C₁₅H₁₅NO
• Molecular Weight: 225.29
• Mol File: 6328-77-4.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 279.5 °C at 760 mmHg
• Flash Point: 165.7 °C
• Appearance: /
• Density: 1.121 g/cm³
• Vapor Pressure: 0.004mmHg at 25°C
• Refractive Index: 1.619
• CAS DataBase Reference: AKOS 243-39(CAS DataBase Reference)
• NIST Chemistry Reference: AKOS 243-39(6328-77-4)
• EPA Substance Registry System: AKOS 243-39(6328-77-4)

Safety Data

• Hazardous Substances Data: 6328-77-4(Hazardous Substances Data)

Usage

Description

AKOS 243-39 is a synthetic steroid derivative with the molecular formula C19H28O2S, used in the manufacturing of pharmaceuticals and research chemicals.

Uses

Used in Pharmaceutical Industry:
AKOS 243-39 is used as an intermediate in the synthesis of pharmaceuticals for its potential biological effects as a steroid derivative.
Used in Research Chemicals:
AKOS 243-39 is used as a research chemical to study its properties and potential applications in the fields of medicine, biochemistry, and drug development.

InChI:InChI=1/C15H15NO/c1-11-8-9-14(12(2)10-11)16-15(17)13-6-4-3-5-7-13/h3-10H,1-2H3,(H,16,17)

Upstream product

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Downstream Products

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• 1383796-97-1 6-methyl-2-phenyl-4H-benzo[d][1,3]oxazine 

Relevant articles and documents

3,6-Di(pyridin-2-yl)-1,2,4,5-tetrazine (pytz) catalysed metal-free amide bond formation from thioacids and amines at room temperature

A 3,6-di(pyridin-2-yl)-1,2,4,5-tetrazine (pytz) catalysed efficient, mild and metal-free method has been developed for direct amide bond synthesis from simple thioacids and amines as starting materials. This methodology is useful for aromatic, aliphatic, and heteroaromatic thioacids as well as primary, secondary, heterocyclic, and even functionalized amines. A wide substrates scope, operationally mild conditions, and acylation of amines without affecting other functional groups such as alcohols, esters, carbodithioates, among others make this strategy very attractive and practical.

Peroxide-mediated direct synthesis of amides from aroyl surrogates

An efficient and metal-free method has been developed for the direct synthesis of amides from readily available azobenzenes reacting with aroyl surrogates such as alcohols, methylarenes. A variety of amides were afforded in moderate to good yields through this reaction. It is another example reported by our group for the use of azobenzene as the new radical acceptor.

Para-Selective C-H Amidation of Simple Arenes with Nitriles

A para-selective C-H amidation of simple arenes with nitriles has been developed. By increasing the amount of arenes, a further meta-selective C-H arylation of the produced amides occurred. Both steric and electronic effects are utilized to control the selectivity, resulting in only para-selective amidation products. The readily available nitriles as amidation reagents instead of amides makes the synthesis of N-arylamides more accessible.