63284-71-9 Usage
Description
Nuarimol is a versatile and effective systemic fungicide that exhibits both curative and protective properties. It is designed to control a broad spectrum of pathogenic fungi, making it a valuable asset in agriculture and other industries. With its ability to target various fungal species, Nuarimol plays a crucial role in safeguarding crops and maintaining their health.
Uses
Used in Agriculture:
Nuarimol is used as a fungicide for the control of a wide range of pathogenic fungi in various crops. This includes cereals, where it is applied as a foliar spray and seed treatment, as well as pome fruits, stone fruits, vines, cucurbits, and other crops. It is particularly effective against powdery mildews, leaf spot, and scab on apples.
Used in Pharmaceutical Industry:
Nuarimol is also utilized in the preparation of difluoroethyl-containing heterocyclic compounds, which are valuable for their antiviral and fungicidal properties. This application highlights the potential of Nuarimol in the development of new drugs and treatments for various diseases.
Used in Environmental Science:
In addition to its agricultural and pharmaceutical applications, Nuarimol is used as a substance in the modeling inhibition of avian aromatase by azole pesticides. This research contributes to a better understanding of the effects of pesticides on wildlife and the environment, ultimately aiding in the development of more sustainable and eco-friendly solutions.
Metabolic pathway
Photolytic degradation is the primary dissipation mechanism of nuarimol
in the environment. Major degradation reactions observed on plants/soil
surfaces and water include hydroxylation of the phenyl groups, oxidation
of the carbinol carbon atom, dehalogenation and carbinol dehydroxylation
(Scheme 1). The primary metabolic pathway of nuarimol in rats
involves mainly aryl hydroxylation (Scheme 2).
Degradation
Nuarimol is stable to hydrolytic degradation when maintained in sterile
buffered solutions (pH 3,6 and 9) in the dark at 52 °C (Saunders, 1977). It
was readily degraded in distilled water via photolysis. The photolytic
DT50 of nuarimol was approximately 1 hour. Numerous photoproducts
were observed; however, no structural characterisation information was
reported (Zornes and Donoho, 1978).
Nuarimol was extensively photodegraded on solid surfaces. More than
80 photodegradation products were observed when nuarimol was
exposed to sunlight on a stainless steel surface for up to 150 hours (Althaus, 1980a). All photoproducts were formed at very low levels (less
than 3% each). The structures of 23 photoproducts were identified. An
abbreviated photodegradation pathway of nuarimol (based on products
accounting for 1% or greater) is presented in Scheme 1. These products
were generated from the following reactions: aryl hydroxylation of the
chlorophenyl and fluorophenyl moieties (to yield 2, 3), cleavage of the
pyrimidine ring and the oxidation of the carbinol carbon atom (4,5) and
dehydroxylation of the carbinol moiety (6). Carboxylic acid fragments
from the phenyl(7,8,9) and pyrimidine moieties (10), resulting from the
cleavage of the parent phenyl and pyrimidine linkages, were also
observed.
Check Digit Verification of cas no
The CAS Registry Mumber 63284-71-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,2,8 and 4 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 63284-71:
(7*6)+(6*3)+(5*2)+(4*8)+(3*4)+(2*7)+(1*1)=129
129 % 10 = 9
So 63284-71-9 is a valid CAS Registry Number.
63284-71-9Relevant articles and documents
Arylphenyl-substituted cyclic keto enols
-
, (2008/06/13)
The present invention relates to novel arylphenyl-substituted cyclic ketoenols, their preparation and the use of such ketoenols as pesticides and/or herbicides. The novel arylphenyl-substituted cyclic ketoenols are of the formula (I) in which CKE refers to the cyclic ketoenol and W, X, Y and Z are as defined in the specification.
